Valentina Carozzi

Assistant Professor

PhD
+39 02 6448 8294
valentina.carozzi1@unimib.it
Valentina Carozzi

Curriculum Vitae

VALENTINA ALDA CAROZZI, ASSISTANT PROFESSOR IN ANATOMY AND HISTOLOGY

SCOPUS Author ID: 23972336300, ORCID ID:  0000-0003-0963-7107 68

EDUCATION

Valentina Alda Carozzi was born in Gallarate (Varese) in 1981. In 2005 she graduated in Medical Biotechnology (110/110 cum laude) and in 2008 she took her PhD in Neuroscience at the University of Milan Bicocca with a project focused on the role of Glutamate in the pathology of the peripheral nervous system.

POSITIONS

2021: Assistant Professor Type B

2017-2021: Assistant Professor Type A

2012-2014: Visiting Researcher at the University of Maryland (Baltimore-USA) and at CNR in Segrate, Milan

2008-2017: Research fellow (Post-doc)

2009-2010: Visiting Researcher at the University of Maryland (Baltimore-USA)

PUBLICATIONS

Dr. Carozzi authored more than 60 peer-reviewed papers (H index 26 Scopus; Citations 2084, update in October 2023)

SELECTED OR INVITED SPEAKER

Dr. Carozzi was selected or invited as presenter at several National and International meetings organized by Peripheral Nerve Society, American Association for Cancer Research, American Society for Clinical Oncology, Glia, International Association for the Study of Pain, Associazione Italiana per lo Studio del Nervo Periferico, Italian Society for Neuroscience, Società Italiana di Anatomia e Istologia, Associazione Italiana per Scienze degli Animali da Laboratorio.

RESEARCH INTERESTS

Since 2008, Dr. Carozzi has been interested in in vivo research in the field of peripheral neurological disorders. She has matured a huge experience in animal studies of peripheral neuropathies and neuropathic pain. She has a coordination and collaboration role in designing and conduction of in vivo experimental protocols as well as in the scientific reporting in all the paradigms performed at Experimental Neurology Unit of the School of Medicine and Surgery. She is also involved in studies based on the effects of synchrotron radiation and X ray-based imaging for peripheral and central nervous system damage. She obtained the qualification for functions A and B for in vivo research, recognized by the Italian Ministry of Health.

SKILLS

Dr. Carozzi personally performs neurophysiological, neuropathological, behavioural and molecular analysis. She developed a xenograft model of human cancer in which the study of the antineoplastic and neurotoxic effects of chemotherapy. She collaborates in the development of new neuroprotective as well as analgesic strategies for chemotherapy-induced peripheral neuropathies and pain relief.

ACTIVE AND PAST RESEARCH COLLABORATIONS

  • CNR Instiute of Neuroscience, Italy (Dr. Antonio Zippo and Dr. Stefano Morara)
  • Johns Hopkins University, Baltimore, USA; (Dr. Barbara Slusher).
  • Johns Hopkins University, Baltimore, USA; (Dr. Ahmet Hoke).
  • Centre on Pain Study, School of Nursing, University of Maryland, Baltimore (MD), USA; (Dr. Susan Dorsey).
  • EISAI Co., Japan; (Dr. Bruce Littlefield).
  • Cytomorphology laboratory, University of Cagliari, Cagliari, ( Marina Quartu).
  • Pain Neurophysiology Centre, CNR Laboratories, Palazzo Lita, Segrate, Milan, (Dr. Gabriele Biella).
  • Istituto Nazionale Neurologico Carlo Besta, Milan, (Dr. Giuseppe Lauria)
  • Dipartimento di Endocrinologia, University of Milan, Milan, (Dr. Roberto Melcangi, Nico Mitro).
  • Neuroscience Institute at Fondazione Cavalieri Ottolenghi, Orbassano, Torino, (Prof. Alessandro Vercelli).

PERSONAL GRANTS

  • 2023-2025: Role of Vice-Principal Investigator in PRIN 2022 PNRR project. Title: “Cortical lateral connectivity in the pathogenesis of neuropathic pain: a target for non-invasive radiosurgical therapies”. Budget 100000 Euros.
  • 2023-2025: Role of Principal investigator in PRIN 2022 project. Title: “The vascular contribution in chemotherapy-induced painful peripheral neuropathy: beyond the neurocentric view and towards novel therapeutic targets”. Budget: 155915 Euros.
  • 2023: University Fund Departmental Fee, Project title: “Studio del ruolo della neoangiogenesi nel sistema nervoso centrale e periferico in modelli sperimentali di dolore cronico”. Budget: 881 Euros
  • 2022: University Fund Departmental Fee, Project title: “Evaluation of microangiogenesis in the central and peripheral nervous system during chemotherapy-induced neuropathic pain”. Budget: 2101 Euros.
  • 2021: University Fund Departmental Fee, Project title: “Morphological, electrophysiological and molecular study of neuron-glia interactions in chemotherapy-induced peripheral neurotoxicity”. Budget: 2134 Euros.
  • 2020: University Fund Departmental Fee, Project title: “Study of the role of glia in the pathogenesis of chemotherapy-induced peripheral neuropathy”. Budget: 2275 Euros.
  • 2019: University Fund Departmental Fee, Project title: “Study of the effect of nitric oxide donor compounds on vincristine-induced peripheral neuropathy in experimental models”. Budget: 2300 Euros.
  • 2015-2017: Role of Principal Investigator in the TRIDEO (Transforming Ideas in Oncological Research) project, “Insights in the mechanisms of oxaliplatin peripheral neurotoxicity”, ID # 15942. Sponsor: AIRC and Fondazione Cariplo. Budget: 97900 Euros.

RECENT AWARDS

  • 2023: invited speaker at SINS Meeting 2023 in Turin.
  • 2021: Prize for “Best scientific contribution” at the ASNP (Italian Peripheral Nerve Association) annual meeting in Monza. Sponsor: ASNP.
  • 2015: Prize for “Best poster presentation” at the annual conference of AISAL (Italian Association of Sciences in Naples. Sponsor: AISAL.
  • 2015: Selected guest at the ceremony for the National Cancer Research Day at the Quirinale Palace, Rome. Sponsor: AIRC.
  • 2014: “Best Pain Research Project” Award at the SIMPAR (Study In Multidisciplinary Pain Research) conference in Rome. Sponsor: “Young Against Pain Group”.

SCIENTIFIC EDITORIAL ACTIVITY

  • 2020-today: Member of the editorial board of the journal “Toxics” (ISSN 2305-6304; CODEN: TOXIC8), impact factor 2020 = 3.3.
  • 2020-21: Co-editor for the scientific journal “Toxics” in the “Special Issue:” Toxic Neuropathy: Mechanisms, Causes, Risk Exposure, Diagnosis, Prevention and Therapeutic Options “.
  • 2014-2016: Co-editor for the scientific journal “Toxics” in the “Special Issue: Toxicities of Therapeutic Agents Used in Medicine”.
  • 2013-today: Reviewer for international peer-reviewed journals including Experimental Neurology (IF 4.6, https://www.journals.elsevier.com/experimental-neurology), Advances in Medical Sciences (IF 2.1, https: / /www.journals.elsevier.com/advances-in-medical-sciences), Current Drug Safety (https://www.currentdrugsafety.com/), European Journal of Neurology (IF 4.4, https: //onlinelibrary.wiley. com / journal / 14681331), Neurotoxicity Research (IF 3.3, ttps: //www.springer.com/journal/12640), Neurological Research (IF 1.2, https://www.springer.com/journal/12640), Neurological Sciences (IF 2.5, https://www.springer.com/journal/10072), Neuroscience Letters (IF, 2.2 https://www.journals.elsevier.com/neuroscience-letters), PlosONE (IF 2.8, https: //journals.plos.org/plosone/s/journal-information), Cancer Chemotherapy and Pharmacology (IF 3, https://www.springer.com/journal/280).
  • 2008 – today: Affiliation to Scientific Societies as Italian Society of Anatomy and Histology (SIAI), Italian Group for the Study of Cytomorphology (GISN), Italian Association for the Study of the Peripheral Nervous System (ASNP), Italian Association for Laboratory Animal Sciences (AISAL), Milan Neuroscience Center, Peripheral Nerve Society (PNS).

NATIONAL SCIENTIFIC QUALIFICATIONS ART. 16, PARAGRAPH 1, LAW 240/2010

Dr. Carozzi obtained the National Scientific Qualifications for the functions of Associate Professor for 05 / H2 Histology (valid from 18/11/2020 to 18/11/2029) and for 05 / H1 Human Anatomy (valid from 12/04/2021 to 12/04/2030).