Curriculum Vitae
Cecilia Ceresa was born in Busto Arsizio (VA) on April 21, 1981. She graduated in Medical Biotechnology (110/110 cum laude) in 2005, and in 2008 she got the PhD in Neuroscience.
In 2006-2007 she joined the laboratories of Professor Godefridus J. Peters of the VU University Medical Centre, Department of Oncology, Netherlands, where she studied the cytotoxic activity of bortezomib and gemcitabine in non-small cell lung cancer cells and the neurotoxic effect of bortezomib, epothilone-B and oxaliplatin.
Since 2006 she is involved in collaborative studies on anticancer activity, drug targeting and chemotherapy-induced neurotoxicity with Research Institutes such as Dipartimento di Ingegneria Chimica e dei Materiali, Università della Calabria, Department of Biotechnology and Biosciences, Università di Milano-Bicocca, Scuola di Scienze e Tecnologie of the University of Camerino.
Since January 2010 she is actively involved in performing joint experiments at the European Synchrotron Radiation Facility (ESRF) in Grenoble, France with Dr. A. Bravin. The collaboration with ESRF deals with pilot in vitro and in vivo experiments devoted to explore innovative strategies to enhance cytotoxicity while reducing neurotoxicity of anticancer drugs.
She is involved in tutor activity of students attending the bachelor degree and the Master of Science in Medical Biotechnology.
She is author of 19 scientific papers on International peer-reviewed journals and 2 book chapters.
RESEARCH INTEREST
- In vitro and in vivo study of antineoplastic agents’ neurotoxicity mechanisms
- In vivo and in vitro study of pharmacological neuroprotection of neurotoxic damage
- Study of the effect of Photon activation therapy on normal and tumoral cells and tissues
- In vitro study of the possible antineoplastic effect of silica nanoparticles
MOST SIGNIFICANT PUBLICATIONS
- Ceresa C, Nicolini G, Semperboni S, Gandin V, Monfrini M, Avezza F, Alberti P, Bravin A, Pellei M, Santini C, Cavaletti G. Evaluation of the Profile and Mechanism of Neurotoxicity of Water-Soluble [Cu(P)4]PF6 and [Au(P)4]PF6 (P = thp or PTA) Anticancer Complexes. Neurotox Res. 2018 Jan 17. doi: 10.1007/s12640-018-9864-8. [Epub ahead of print]
- Manodoro S, Spelzini F, Cesana MC, Frigerio M, Maggioni D, Ceresa C, Penati C, Sicuri M, Fruscio R, Nicolini G, Milani R. Histologic and metabolic assessment in a cohort of patients with genital prolapse: preoperative stage and recurrence investigations. Minerva Ginecol. 2017 Jun;69(3):233-238. doi: 10.23736/S0026-4784.16.03977-0. Epub 2016 Sep 21.
- Gandin V, Ceresa C, Esposito G, Indraccolo S, Porchia M, Tisato F, Santini C, Pellei M, Marzano C. Therapeutic potential of the phosphino Cu(I) complex (HydroCuP) in the treatment of solid tumors. Sci Rep. 2017 Oct 24;7(1):13936. doi: 10.1038/s41598-017-13698-1.
- Manodoro S, Spelzini F, Cesana MC, Frigerio M, Maggioni D, Ceresa C, Penati C, Sicuri M, Fruscio R, Nicolini G, Milani R. Histologic and metabolic assessment in a cohort of patients with genital prolapse: preoperative stage and recurrence investigations. Minerva Ginecol. 2017 Jun;69(3):233-238. doi: 10.23736/S0026-4784.16.03977-0. Epub 2016 Sep 21.
- Ceresa C, Nicolini G, Semperboni S, Requardt H, Le Duc G, Santini C, Pellei M, Bentivegna A, Dalprà L, Cavaletti G, Bravin A. Synchrotron-based photon activation therapy effect on cisplatin pre-treated human glioma stem cells. Anticancer Res. 2014 Oct;34(10):5351-5.
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