NanoCosPha – laboratories presentation

Researchers involved in the NanoCosPha consortium present the laboratories and the technologies implemented for the project (audio in italian only)

Gold nanoparticles intracellular distribution

MDA-MB231 human cancer breast cells treated with gold nanopaticles (size: 15 nm diameter). The intracellular distribution of the gold nanoparticles (bright white in the video) has been imaged with Nanolive for 16 hours..


Tudda A, Donzelli E, Nicolini G, et al. Breast radiotherapy with kilovoltage photons and gold nanoparticles as radiosensitizer: An in vitro study. Med Phys. 2022;49(1):568-578. doi:10.1002/mp.15348

Sciatic Nerve

acquired with a ZEISS GeminiSEM 300 equipped with SBF system

Human spinal cord and column anatomy by synchrotron X-ray 3D neuroimaging

Illustration of the main results of the research project on the investigation of the human spinal cord and column anatomy by synchrotron X-ray 3D neuroimaging: first the high resolution computed tomography data (46^3 μm^3 voxel size) and 3D rendering of an extended Thiel-embalmed human spinal column specimen, followed by the computed tomography data (8^3 μm^3 voxel size) and 3D rendering of a portion of a formalin-fixed human spinal cord specimen. Images acquired at the Medical Beamline ID17, ESRF, Grenoble, France.


“High-spatial-resolution three-dimensional imaging of human spinal cord and column anatomy with postmortem X-ray phase-contrast micro-CT” G. E. Barbone (a, b), A. Bravin (c), A. Mittone (c), S. Grosu (b), J. Ricke (b), G. Cavaletti (d, e), Valentin Djonov (f), Paola Coan (a,b) Radiology, 2020; doi: 10.1148/radiol.2020201622
(a) Faculty of Physics, Ludwig-Maximilians-Universität München (Germany)
(b) Department of Radiology, University Hospital, Ludwig-Maximilians-Universität München (Germany)
(c) European Synchrotron Radiation Facility (France)
(d) School of Medicine and Surgery, University of Milano-Bicocca (Italy)
(e) Milan Center for Neuroscience, University of Milano-Bicocca (Italy) (f) Institute of Anatomy, University of Bern (Switzerland)
Supported by the Deutsche Forschungsgemeinschaft (Cluster of Excellence)-Munich Center for Advanced Photonics (EXE158), International Max Plank Research School of Advanced Photon Science (IMPRS-APS), and European COST Action CA16122 in the form of a networking STSM Travel Grant.

Talk:  Chemotherapy-induced peripheral neurotoxicity

In The Biomedical & Life Sciences Collection, Henry Stewart Talks.

Retrieved February 28, 2020, from

Peripheral nervous system clinical examination

Neurons in 3D culture

3D culture of Adult mouse Dorsal Root Ganglia Neurons in collagen gel labeled with Tuj1 (green) and propidium iodide (red)