Media

NanoCosPha – laboratories presentation

Researchers involved in the NanoCosPha consortium present the laboratories and the technologies implemented for the project (audio in italian only)

Gold nanoparticles intracellular distribution

MDA-MB231 human cancer breast cells treated with gold nanopaticles (size: 15 nm diameter). The intracellular distribution of the gold nanoparticles (bright white in the video) has been imaged with Nanolive for 16 hours..

Publication:

Tudda A, Donzelli E, Nicolini G, et al. Breast radiotherapy with kilovoltage photons and gold nanoparticles as radiosensitizer: An in vitro study. Med Phys. 2022;49(1):568-578. doi:10.1002/mp.15348


Sciatic Nerve

acquired with a ZEISS GeminiSEM 300 equipped with SBF system

Human spinal cord and column anatomy by synchrotron X-ray 3D neuroimaging

Illustration of the main results of the research project on the investigation of the human spinal cord and column anatomy by synchrotron X-ray 3D neuroimaging: first the high resolution computed tomography data (46^3 μm^3 voxel size) and 3D rendering of an extended Thiel-embalmed human spinal column specimen, followed by the computed tomography data (8^3 μm^3 voxel size) and 3D rendering of a portion of a formalin-fixed human spinal cord specimen. Images acquired at the Medical Beamline ID17, ESRF, Grenoble, France.

Publication:

“High-spatial-resolution three-dimensional imaging of human spinal cord and column anatomy with postmortem X-ray phase-contrast micro-CT” G. E. Barbone (a, b), A. Bravin (c), A. Mittone (c), S. Grosu (b), J. Ricke (b), G. Cavaletti (d, e), Valentin Djonov (f), Paola Coan (a,b) Radiology, 2020; doi: 10.1148/radiol.2020201622
(a) Faculty of Physics, Ludwig-Maximilians-Universität München (Germany)
(b) Department of Radiology, University Hospital, Ludwig-Maximilians-Universität München (Germany)
(c) European Synchrotron Radiation Facility (France)
(d) School of Medicine and Surgery, University of Milano-Bicocca (Italy)
(e) Milan Center for Neuroscience, University of Milano-Bicocca (Italy) (f) Institute of Anatomy, University of Bern (Switzerland)
Supported by the Deutsche Forschungsgemeinschaft (Cluster of Excellence)-Munich Center for Advanced Photonics (EXE158), International Max Plank Research School of Advanced Photon Science (IMPRS-APS), and European COST Action CA16122 in the form of a networking STSM Travel Grant.

Talk:  Chemotherapy-induced peripheral neurotoxicity

In The Biomedical & Life Sciences Collection, Henry Stewart Talks.

Retrieved February 28, 2020, from https://hstalks.com/bs/4159/.


Peripheral nervous system clinical examination


Neurons in 3D culture

3D culture of Adult mouse Dorsal Root Ganglia Neurons in collagen gel labeled with Tuj1 (green) and propidium iodide (red)