Recent publications
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2021
Alberti P, Bernasconi DP, Cornblath DR, Merkies ISJ, Park SB, Velasco R, Bruna J, Psimaras D, Koeppen S, Pace A, Dorsey SG, Argyriou AA, Kalofonos HP, Briani C, Schenone A, Faber CG, Mazzeo A, Grisold W, Valsecchi M, Cavaletti G; CI-PeriNomS group. Prospective Evaluation of Health Care Provider and Patient Assessments in Chemotherapy-Induced Peripheral Neurotoxicity. Neurology. 2021 Aug 17;97(7):e660-e672. doi: 10.1212/WNL.0000000000012300. Epub 2021 Jun 2. PMID: 34078718
Alberti P, Canta A, Chiorazzi A, Fumagalli G, Meregalli C, Monza L, Pozzi E, Ballarini E, Rodriguez-Menendez V, Oggioni N, Sancini G, Marmiroli P, Cavaletti G. Topiramate prevents oxaliplatin-related axonal hyperexcitability and oxaliplatin induced peripheral neurotoxicity. Neuropharmacology. 2020 Mar 1;164:107905. doi: 10.1016/j.neuropharm.2019.107905. Epub 2019 Dec 4. PMID: 31811874
Alberti P, Lehmann HC. Chemotherapy induced peripheral neurotoxicity: Six essential articles for effective future research. Exp Neurol. 2021 Mar;337:113555. doi: 10.1016/j.expneurol.2020.113555. Epub 2020 Dec 13. PubMed PMID: 33340795.
Argyriou AA, Karteri S, Bruna J, Mariotto S, Simo M, Velissaris D, Kalofonou F, Cavaletti G, Ferrari S, Kalofonos HP. Serum neurofilament light chain levels as biomarker of paclitaxel-induced cognitive impairment in patients with breast cancer: a prospective study. Support Care Cancer. 2022 Feb;30(2):1807-1814. doi: 10.1007/s00520-021-06509-x. Epub 2021 Oct 2. PMID: 34599664
Barbone GE, Bravin A, Mittone A, Grosu S, Ricke J, Cavaletti G, Djonov V, Coan P. High-Spatial-Resolution Three-dimensional Imaging of Human Spinal Cord and Column Anatomy with Postmortem X-ray Phase-Contrast Micro-CT. Radiology. 2021 Jan;298(1):135-146. doi: 10.1148/radiol.2020201622. Epub 2020 Oct 27. PMID: 33107800
Baroncini D, Simone M, Iaffaldano P, Brescia Morra V, Lanzillo R, Filippi M, Romeo M, Patti F, Chisari CG, Cocco E, Fenu G, Salemi G, Ragonese P, Inglese M, Cellerino M, Margari L, Comi G, Zaffaroni M, Ghezzi A; Italian MS registry. Risk of Persistent Disability in Patients With Pediatric-Onset Multiple Sclerosis. JAMA Neurol. 2021 Jun 1;78(6):726-735. doi: 10.1001/jamaneurol.2021.1008. PMID: 33938921
Bonomo R, Cavaletti G. Clinical and biochemical markers in CIPN: A reappraisal. Rev Neurol (Paris). 2021 Oct;177(8):890-907. doi: 10.1016/j.neurol.2020.11.001. Epub 2021 Feb 26. PMID: 33648782 Review.
Borgo F, Macandog AD, Diviccaro S, Falvo E, Giatti S, Cavaletti G, Melcangi RC. Alterations of gut microbiota composition in post-finasteride patients: a pilot study. J Endocrinol Invest. 2021 Jun;44(6):1263-1273. doi: 10.1007/s40618-020-01424-0. Epub 2020 Sep 19. PMID: 32951160
Canta A, Chiorazzi A, Pozzi E, Fumagalli G, Monza L, Meregalli C, Carozzi VA, Rodriguez-Menendez V, Oggioni N, Näsström J, Marmiroli P, Cavaletti G. Calmangafodipir Reduces Sensory Alterations and Prevents Intraepidermal Nerve Fibers Loss in a Mouse Model of Oxaliplatin Induced Peripheral Neurotoxicity. Antioxidants (Basel). 2020 Jul 7;9(7):594. doi: 10.3390/antiox9070594. PMID: 32645985
Carozzi VA, Bolino A, D’Antonio M, Quattrini A, Cavaletti G. Nerve pathology in animal models of neuropathies. J Peripher Nerv Syst. 2021 Nov;26 Suppl 2:S61-S68. doi: 10.1111/jns.12463. Epub 2021 Sep 9. PMID: 34498774
Carozzi VA, Salio C, Rodriguez-Menendez V, Ciglieri E, Ferrini F. 2D vs 3D morphological analysis of dorsal root ganglia in health and painful neuropathy. Eur J Histochem. 2021 Oct 19;65(s1):3276. doi: 10.4081/ejh.2021.3276.PMID: 34664808
Cavaletti G, Marmiroli P, Renn CL, Dorsey SG, Serra MP, Quartu M, Meregalli C. Cannabinoids: an Effective Treatment for Chemotherapy-Induced Peripheral Neurotoxicity? Neurotherapeutics. 2021 Oct 19. doi: 10.1007/s13311-021-01127-1. Online ahead of print. PMID: 34668147
De Caro R, Boscolo-Berto R, Artico M, Bertelli E, Cannas M, Cappello F, Carpino G, Castorina S, Cataldi A, Cavaletti GA, Cinti S, Cocco LI, Cremona O, Crivellato E, De Luca A, Falconi M, Familiari G, Ferri GL, Fornai F, Gesi M, Geuna S, Gibelli DM, Giordano A, Gobbi P, Guerra G, Gulisano M, Macchi V, Macchiarelli G, Manzoli L, Michetti F, Miscia S, Montagnani S, Montella ACM, Morini S, Onori P, Palumbo C, Papa M, Porzionato A, Quacci DE, Raspanti M, Rende M, Rezzani R, Ribatti D, Ripani M, Rodella LF, Rossi P, Sbarbati A, Secchiero P, Sforza C, Stecco C, Toni R, Vercelli A, Vitale M, Zancanaro C, Zauli G, Zecchi S, Anastasi GP, Gaudio E. The Italian law on body donation: A position paper of the Italian College of Anatomists. Ann Anat. 2021 Nov;238:151761. doi: 10.1016/j.aanat.2021.151761. Epub 2021 Jun 15. PMID: 34139280
Doets AY, Lingsma HF, Walgaard C, Islam B, Papri N, Davidson A, Yamagishi Y, Kusunoki S, Dimachkie MM, Waheed W, Kolb N, Islam Z, Mohammad QD, Harbo T, Sindrup SH, Chavada G, Willison HJ, Casasnovas C, Bateman K, Miller JA, van den Berg B, Verboon C, Roodbol J, Leonhard SE, Benedetti L, Kuwabara S, Van den Bergh P, Monges S, Marfia GA, Shahrizaila N, Galassi G, Péréon Y, Bürmann J, Kuitwaard K, Kleyweg RP, Marchesoni C, Sedano Tous MJ, Querol L, Illa I, Wang Y, Nobile-Orazio E, Rinaldi S, Schenone A, Pardo J, Vermeij FH, Lehmann HC, Granit V, Cavaletti G, Gutiérrez-Gutiérrez G, Barroso FA, Visser LH, Katzberg HD, Dardiotis E, Attarian S, van der Kooi AJ, Eftimov F, Wirtz PW, Samijn JP, Gilhuis HJ, Hadden RD, Holt JK, Sheikh KA, Karafiath S, Vytopil M, Antonini G, Feasby TE, Faber CG, Gijsbers CJ, Busby M, Roberts RC, Silvestri NJ, Fazio R, van Dijk GW, Garssen MP, Straathof CS, Gorson KC, Jacobs BC; IGOS Consortium. Predicting Outcome in Guillain-Barré Syndrome: International Validation of the Modified Erasmus GBS Outcome Score. Neurology. 2021 Dec 22:10.1212/WNL.0000000000013139. doi: 10.1212/WNL.0000000000013139. Online ahead of print. PMID: 34937789
Eldridge S, Scuteri A, Jones EMC, Cavaletti G, Guo L, Glaze E. Considerations for a Reliable In Vitro Model of Chemotherapy-Induced Peripheral Neuropathy. Toxics. 2021 Nov 11;9(11):300. doi: 10.3390/toxics9110300. PMID: 34822690
Fumagalli G, Monza L, Cavaletti G, Rigolio R, Meregalli C. Neuroinflammatory Process Involved in Different Preclinical Models of Chemotherapy-Induced Peripheral Neuropathy. Front Immunol. 2021 Feb 4;11:626687. doi: 10.3389/fimmu.2020.626687. eCollection 2020.
Giambra M, Messuti E, Di Cristofori A, Cavandoli C, Bruno R, Buonanno R, Marzorati M, Zambuto M, Rodriguez-Menendez V, Redaelli S, Giussani C, Bentivegna A. Characterizing the Genomic Profile in High-Grade Gliomas: From Tumor Core to Peritumoral Brain Zone, Passing through Glioma-Derived Tumorspheres. Biology (Basel). 2021 Nov 9;10(11):1157. doi: 10.3390/biology10111157.PMID: 34827152
Huang KM, Leblanc AF, Uddin ME, Kim JY, Chen M, Eisenmann ED, Gibson AA, Li Y, Hong KW, DiGiacomo D, Xia SH, Alberti P, Chiorazzi A, Housley SN, Cope TC, Sprowl JA, Wang J, Loprinzi CL, Noonan A, Lustberg MB, Cavaletti G, Pabla N, Hu S, Sparreboom A. Neuronal uptake transporters contribute to oxaliplatin neurotoxicity in mice. J Clin Invest. 2020 Sep 1;130(9):4601-4606. doi: 10.1172/JCI136796.PMID: 32484793
Lepore V, Bosetti C, Santucci C, Iaffaldano P, Trojano M, Mosconi P; Italian Multiple Sclerosis Register Centers Group, the Scientific Committee of Italian SM Register. Detection of disability worsening in relapsing-remitting multiple sclerosis patients: a real-world roving Expanded Disability Status Scale reference analysis from the Italian Multiple Sclerosis Register. Eur J Neurol. 2021 Feb;28(2):567-578. doi: 10.1111/ene.14589. Epub 2020 Nov 6. PMID: 33058344
Liberatore G, Manganelli F, Doneddu PE, Cocito D, Fazio R, Briani C, Filosto M, Benedetti L, Mazzeo A, Antonini G, Cosentino G, Jann S, Cortese A, Marfia GA, Clerici AM, Siciliano G, Carpo M, Luigetti M, Lauria G, Rosso T, Cavaletti G, Santoro L, Peci E, Tronci S, Ruiz M, Cotti Piccinelli S, Schenone A, Leonardi L, Toscano A, Mataluni G, Spina E, Gentile L, Nobile-Orazio E; Italian CIDP Database Study Group. Chronic inflammatory demyelinating polyradiculoneuropathy: can a diagnosis be made in patients not fulfilling electrodiagnostic criteria? Eur J Neurol. 2021 Feb;28(2):620-629. doi: 10.1111/ene.14545. Epub 2020 Oct 15. PMID: 32959475
Luijten LWG, Leonhard SE, van der Eijk AA, Doets AY, Appeltshauser L, Arends S, Attarian S, Benedetti L, Briani C, Casasnovas C, Castellani F, Dardiotis E, Echaniz-Laguna A, Garssen MPJ, Harbo T, Huizinga R, Humm AM, Jellema K, van der Kooi AJ, Kuitwaard K, Kuntzer T, Kusunoki S, Lascano AM, Martinez-Hernandez E, Rinaldi S, Samijn JPA, Scheidegger O, Tsouni P, Vicino A, Visser LH, Walgaard C, Wang Y, Wirtz PW, Ripellino P, Jacobs BC; IGOS consortium. Guillain-Barré syndrome after SARS-CoV-2 infection in an international prospective cohort study. Brain. 2021 Dec 16;144(11):3392-3404. doi: 10.1093/brain/awab279. PMID: 34553216
Malacrida A, Cavaletti G, Miloso M. Rigosertib and Cholangiocarcinoma: A Cell Cycle Affair. Int J Mol Sci. 2021 Dec 25;23(1):213. doi: 10.3390/ijms23010213. PMID: 35008638.
Malacrida A, Cavalloro V, Martino E, Costa G, Ambrosio FA, Alcaro S, Rigolio R, Cassetti A, Miloso M, Collina S. Anti-Multiple Myeloma Potential of Secondary Metabolites from Hibiscus sabdariffa-Part 2. Molecules. 2021 Oct 31;26(21):6596. doi: 10.3390/molecules26216596. PMID: 34771006
Malacrida A, Rigolio R, Celio L, Damian S, Cavaletti G, Mazzaferro V, Miloso M. In Vitro Evaluation of Rigosertib Antitumoral and Radiosensitizing Effects against Human Cholangiocarcinoma Cells. Int J Mol Sci. 2021 Jul 30;22(15):8230. doi: 10.3390/ijms22158230. PMID: 34360994
Malacrida A, Semperboni S, Di Domizio A, Palmioli A, Broggi L, Airoldi C, Meregalli C, Cavaletti G, Nicolini G. Tubulin binding potentially clears up Bortezomib and Carfilzomib differential neurotoxic effect. Sci Rep. 2021 May 18;11(1):10523. doi: 10.1038/s41598-021-89856-3. PMID: 34006972
Meregalli C, Bonomo R, Cavaletti G, Carozzi VA. Blood molecular biomarkers for chemotherapy-induced peripheral neuropathy: From preclinical models to clinical practice. Neurosci Lett. 2021 Apr 1;749:135739. doi: 10.1016/j.neulet.2021.135739. Epub 2021 Feb 15. PMID: 33600907 Review.
Meregalli C, Fumagalli G, Alberti P, Canta A, Chiorazzi A, Monza L, Pozzi E, Carozzi VA, Blennow K, Zetterberg H, Cavaletti G, Marmiroli P. Neurofilament light chain: a specific serum biomarker of axonal damage severity in rat models of Chemotherapy-Induced Peripheral Neurotoxicity. Arch Toxicol. 2020 Jul;94(7):2517-2522. doi: 10.1007/s00204-020-02755-w. Epub 2020 Apr 24. PMID: 32333051
Meregalli C, Maricich Y, Cavaletti G, Canta A, Carozzi VA, Chiorazzi A, Newbold E, Marmiroli P, Ceresa C, Diani A, Papapetropoulos S, Lee MS. Reversal of Bortezomib-Induced Neurotoxicity by Suvecaltamide, a Selective T-Type Ca-Channel Modulator, in Preclinical Models. Cancers (Basel). 2021 Oct 7;13(19):5013. doi: 10.3390/cancers13195013. PMID: 34638498
Meregalli C, Monza L, Chiorazzi A, Scali C, Guarnieri C, Fumagalli G, Alberti P, Pozzi E, Canta A, Ballarini E, Rodriguez-Menendez V, Oggioni N, Cavaletti G, Marmiroli P. Human Intravenous Immunoglobulin Alleviates Neuropathic Symptoms in a Rat Model of Paclitaxel-Induced Peripheral Neurotoxicity. Int J Mol Sci. 2021 Jan 21;22(3):1058. doi:10.3390/ijms22031058. PMID: 33494384
Monza L, Fumagalli G, Chiorazzi A, Alberti P. Addressing the Need of a Translational Approach in Peripheral Neuropathy Research: Morphology Meets Function. Brain Sci. 2021 Jan 22;11(2). doi: 10.3390/brainsci11020139. PubMed PMID: 33499072; PubMed Central PMCID: PMC7911498.
Monza L, Fumagalli G, Chiorazzi A, Alberti P. Translating morphology from bench side to bed side via neurophysiology: 8-min protocol for peripheral neuropathy research. J Neurosci Methods. 2021 Nov 1;363:109323. doi: 10.1016/j.jneumeth.2021.109323. Epub 2021 Aug 13. PMID: 34391792
Park SB, Tamburin S, Schenone A, Kleckner IR, Velasco R, Alberti P, Kanzawa-Lee G, Lustberg M, Dorsey SG, Mantovani E, Hamedani M, Argyriou AA, Cavaletti G, Hoke A. Optimal outcome measures for assessing exercise and rehabilitation approaches in chemotherapy-induced peripheral-neurotoxicity: Systematic review and consensus expert opinion. Expert Rev Neurother. 2022 Jan 11;:1-12. doi: 10.1080/14737175.2022.2018300. [Epub ahead of print] PubMed PMID: 34894974.
Pero ME, Meregalli C, Qu X, Shin GJ, Kumar A, Shorey M, Rolls MM, Tanji K, Brannagan TH, Alberti P, Fumagalli G, Monza L, Grueber WB, Cavaletti G, Bartolini F. Pathogenic role of delta 2 tubulin in bortezomib-induced peripheral neuropathy. Proc Natl Acad Sci U S A. 2021 Jan 26;118(4). doi: 10.1073/pnas.2012685118. PubMed PMID: 33468672; PubMed Central PMCID: PMC7848563. PMID: 33613570
Potenzieri A, Riva B, Rigolio R, Chiorazzi A, Pozzi E, Ballarini E, Cavaletti G, Genazzani AA. Oxaliplatin-induced neuropathy occurs through impairment of haemoglobin proton buffering and is reversed by carbonic anhydrase inhibitors. Pain. 2020 Feb;161(2):405-415. doi: 10.1097/j.pain.0000000000001722. PMID: 31634341
Pozzi E, Fumagalli G, Chiorazzi A, Canta A, Cavaletti G. Genetic factors influencing the development of vincristine-induced neurotoxicity. Expert Opin Drug Metab Toxicol. 2021 Feb;17(2):215-226. doi: 10.1080/17425255.2021.1855141. Epub 2020 Dec 6. PMID: 33283553 Review.
Pozzi E, Fumagalli G, Chiorazzi A, Canta A, Meregalli C, Monza L, Carozzi VA, Oggioni N, Rodriguez-Menendez V, Cavaletti G, Marmiroli P. The relevance of multimodal assessment in experimental oxaliplatin-induced peripheral neurotoxicity. Exp Neurol. 2020 Dec;334:113458. doi: 10.1016/j.expneurol.2020.113458. Epub 2020 Sep 2. PMID: 32889007
Smith EML, Kuisell C, Cho Y, Kanzawa-Lee GA, Gilchrist LS, Park SB, Scott MR, Alberti P. Characteristics and patterns of pediatric chemotherapy-induced peripheral neuropathy: A systematic review. Cancer Treat Res Commun. 2021;28:100420. doi: 10.1016/j.ctarc.2021.100420. Epub 2021 Jun 8. Review. PubMed PMID: 34225104.
Spina E, Doneddu PE, Liberatore G, Cocito D, Fazio R, Briani C, Filosto M, Benedetti L, Antonini G, Cosentino G, Jann S, Mazzeo A, Cortese A, Marfia GA, Clerici AM, Siciliano G, Carpo M, Luigetti M, Lauria G, Rosso T, Cavaletti G, Peci E, Tronci S, Ruiz M, Piccinelli SC, Schenone A, Leonardi L, Gentile L, Piccolo L, Mataluni G, Santoro L, Nobile-Orazio E, Manganelli F; on the behalf of the Italian CIDP Database Study Group. The neurophysiological lesson from the Italian CIDP database. Neurol Sci. 2022 Jan;43(1):573-582. doi: 10.1007/s10072-021-05321-z. Epub 2021 May 21. PMID: 34021439
Spina E, Doneddu PE, Liberatore G, Cocito D, Fazio R, Briani C, Filosto M, Benedetti L, Antonini G, Cosentino G, Jann S, Mazzeo A, Cortese A, Marfia GA, Clerici AM, Siciliano G, Carpo M, Luigetti M, Lauria G, Rosso T, Cavaletti G, Peci E, Tronci S, Ruiz M, Piccinelli SC, Schenone A, Leonardi L, Gentile L, Piccolo L, Mataluni G, Santoro L, Nobile-Orazio E, Manganelli F; Italian CIDP Database Study Group. Prolonged distal motor latency of median nerve does not improve diagnostic accuracy for CIDP. J Neurol. 2021 Jun 26. doi: 10.1007/s00415-021-10672-w. Online ahead of print. PMID: 34173874
Streckmann F, Balke M, Cavaletti G, Toscanelli A, Bloch W, Décard BF, Lehmann HC, Faude O. Exercise and Neuropathy: Systematic Review with Meta-Analysis. Sports Med. 2021 Dec 29. doi: 10.1007/s40279-021-01596-6. Online ahead of print. PMID: 34964950
Tamburin S, Park SB, Schenone A, Mantovani E, Hamedani M, Alberti P, Yildiz-Kabak V, Kleckner IR, Kolb N, Mazzucchelli M, McNeish BL, Argyriou AA, Cavaletti G, Hoke A; Toxic Neuropathy Consortium. Rehabilitation, exercise, and related non-pharmacological interventions for chemotherapy-induced peripheral neurotoxicity: Systematic review and evidence-based recommendations. Crit Rev Oncol Hematol. 2021 Dec 28:103575. doi: 10.1016/j.critrevonc.2021.103575. Online ahead of print. PMID: 34968623 Review.
Tarasiuk O, Cavaletti G, Meregalli C. Clinical and preclinical features of eribulin-related peripheral neuropathy. Exp Neurol. 2022 Feb;348:113925. doi: 10.1016/j.expneurol.2021.113925. Epub 2021 Nov 18. PMID: 34801586
Tudda A, Donzelli E, Nicolini G, Semperboni S, Bossi M, Cavaletti G, Castriconi R, Mangili P, Vecchio AD, Sarno A, Mettivier G, Russo P. Breast radiotherapy with kilovoltage photons and gold nanoparticles as radiosensitizer: An in vitro study. Med Phys. 2022 Jan;49(1):568-578. doi: 10.1002/mp.15348. Epub 2021 Dec 1. PMID: 34778990
Verboon C, Harbo T, Cornblath DR, Hughes RAC, van Doorn PA, Lunn MP, Gorson KC, Barroso F, Kuwabara S, Galassi G, Lehmann HC, Kusunoki S, Reisin RC, Binda D, Cavaletti G, Jacobs BC; IGOS consortium; GOS consortium. Intravenous immunoglobulin treatment for mild Guillain-Barré syndrome: an international observational study. J Neurol Neurosurg Psychiatry. 2021 Oct;92(10):1080-1088. doi: 10.1136/jnnp-2020-325815. Epub 2021 Jun 8. PMID: 34103340
2020
Doneddu PE, Bianchi E, Cocito D, Manganelli F, Fazio R, Filosto M, Mazzeo A, Cosentino G, Cortese A, Jann S, Clerici AM, Antonini G, Siciliano G, Luigetti M, Marfia GA, Briani C, Lauria G, Rosso T, Cavaletti G, Carpo M, Benedetti L, Beghi E, Liberatore G, Santoro L, Peci E, Tronci S, Cotti Piccinelli S, Toscano A, Piccolo L, Verrengia EP, Leonardi L, Schirinzi E, Mataluni G, Ruiz M, Dacci P, Nobile-Orazio E; Italian CIDP Database Study Group. Risk factors for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP): antecedent events, lifestyle and dietary habits. Data from the Italian CIDP Database. Eur J Neurol. 2020 Jan;27(1):136-143. doi: 10.1111/ene.14044. Epub 2019 Aug 9. PMID: 31325350.
Arosio A, Cristofani R, Pansarasa O, Crippa V, Riva C, Sirtori R, Rodriguez-Menendez V, Riva N, Gerardi F, Lunetta C, Cereda C, Poletti A, Ferrarese C, Tremolizzo L, Sala G. HSC70 expression is reduced in lymphomonocytes of sporadic ALS patients and contributes to TDP-43 accumulation. Amyotroph Lateral Scler Frontotemporal Degener. 2020 Feb;21(1-2):51-62. doi: 10.1080/21678421.2019.1672749. Epub 2019 Oct 30. PMID: 31663379.
Verboon C, van den Berg B, Cornblath DR, Venema E, Gorson KC, Lunn MP, Lingsma H, Van den Bergh P, Harbo T, Bateman K, Pereon Y, Sindrup SH, Kusunoki S, Miller J, Islam Z, Hartung HP, Chavada G, Jacobs BC, Hughes RAC, van Doorn PA; IGOS Consortium. Original research: Second IVIg course in Guillain-Barré syndrome with poor prognosis: the non-randomised ISID study. J Neurol Neurosurg Psychiatry. 2020 Feb;91(2):113-121. doi: 10.1136/jnnp-2019-321496. Epub 2019 Oct 5. PMID: 31586949.
Potenzieri A, Riva B, Rigolio R, Chiorazzi A, Pozzi E, Ballarini E, Cavaletti G, Genazzani AA. Oxaliplatin-induced neuropathy occurs through impairment of haemoglobin proton buffering and is reversed by carbonic anhydrase inhibitors . Pain. 2020 Feb;161(2):405-415. doi: 10.1097/j.pain.0000000000001722. PMID: 31634341.
Malacrida A, Rivara M, Di Domizio A, Cislaghi G, Miloso M, Zuliani V, Nicolini G. 3D proteome-wide scale screening and activity evaluation of a new ALKBH5 inhibitor in U87 glioblastoma cell line. Bioorg Med Chem. 2020 Feb 15;28(4):115300. doi: 10.1016/j.bmc.2019.115300. Epub 2019 Dec 30. PMID: 31937477.
Calls A, Carozzi V, Navarro X, Monza L, Bruna J. Pathogenesis of platinum-induced peripheral neurotoxicity: Insights from preclinical studies. Exp Neurol. 2020 Mar;325:113141. doi: 10.1016/j.expneurol.2019.113141. Epub 2019 Dec 19. PMID: 31865195.
Bruna J, Alberti P, Calls-Cobos A, Caillaud M, Damaj MI, Navarro X. Methods for in vivo studies in rodents of chemotherapy induced peripheral neuropathy. Exp Neurol. 2020 Mar;325:113154. doi: 10.1016/j.expneurol.2019.113154. Epub 2019 Dec 15. PMID: 31837318; PMCID: PMC7105293.
Alberti P, Canta A, Chiorazzi A, Fumagalli G, Meregalli C, Monza L, Pozzi E, Ballarini E, Rodriguez-Menendez V, Oggioni N, Sancini G, Marmiroli P, Cavaletti G. Topiramate prevents oxaliplatin-related axonal hyperexcitability and oxaliplatin induced peripheral neurotoxicity. Neuropharmacology. 2020 Mar 1;164:107905. doi: 10.1016/j.neuropharm.2019.107905. Epub 2019 Dec 4. PMID: 31811874.
Fumagalli G, Monfrini M, Donzelli E, Rodriguez-Menendez V, Bonandrini B, Figliuzzi M, Remuzzi A, D’Amico G, Cavaletti G, Scuteri A. Protective Effect of Human Mesenchymal Stem Cells on the Survival of Pancreatic Islets. Int J Stem Cells. 2020 Mar 30;13(1):116-126. doi: 10.15283/ijsc19094. PMID: 31887847; PMCID: PMC7119207.
Alberti P, Beretta S, Piatti M, Karantzoulis A, Piatti ML, Santoro P, Viganò M, Giovannelli G, Pirro F, Montisano DA, Appollonio I, Ferrarese C. Guillain-Barré syndrome related to COVID-19 infection. Neurol Neuroimmunol Neuroinflamm. 2020 Apr 29;7(4):e741. doi: 10.1212/NXI.0000000000000741. PMID: 32350026; PMCID: PMC7217652.
Milani C, Farina F, Botto L, Massimino L, Lonati E, Donzelli E, Ballarini E, Crippa L, Marmiroli P, Bulbarelli A, Palestini P. Systemic Exposure to Air Pollution Induces Oxidative Stress and Inflammation in Mouse Brain, Contributing to Neurodegeneration Onset . Int J Mol Sci. 2020 May 24;21(10):3699. doi: 10.3390/ijms21103699. PMID: 32456361; PMCID: PMC7279458.
Donzelli E, Scuteri A. Mesenchymal Stem Cells: A Trump Card for the Treatment of Diabetes? Biomedicines. 2020 May 6;8(5):112. doi: 10.3390/biomedicines8050112. PMID: 32384630; PMCID: PMC7277294.
Giatti S, Rigolio R, Diviccaro S, Falvo E, Caruso D, Garcia-Segura LM, Cavaletti G, Melcangi RC. Sex dimorphism in an animal model of multiple sclerosis: Focus on pregnenolone synthesis. J Steroid Biochem Mol Biol. 2020 May;199:105596. doi: 10.1016/j.jsbmb.2020.105596. Epub 2020 Jan 17. PMID: 31958635.
Gironi M, Dalla-Costa G, Frigo M, Rovaris M, Clerici M, Bazzini C, Andreoni S, Comi G, Furlan R, Ferrarese C, Cavaletti G, Saresella M, Zoia CP. Platelet glutamate uptake and Th1 cells inversely correlate in relapsing/remitting and in progressive multiple sclerosis . Mult Scler Relat Disord. 2020 Jun;41:102007. doi: 10.1016/j.msard.2020.102007. Epub 2020 Feb 13. PMID: 32092504.
Meregalli C, Fumagalli G, Alberti P, Canta A, Chiorazzi A, Monza L, Pozzi E, Carozzi VA, Blennow K, Zetterberg H, Cavaletti G, Marmiroli P. Neurofilament light chain: a specific serum biomarker of axonal damage severity in rat models of Chemotherapy-Induced Peripheral Neurotoxicity. Arch Toxicol. 2020 Jul;94(7):2517-2522. doi: 10.1007/s00204-020-02755-w. Epub 2020 Apr 24. PMID: 32333051.
Barbone GE, Bravin A, Mittone A, Kraiger MJ, Hrabě de Angelis M, Bossi M, Ballarini E, Rodriguez-Menendez V, Ceresa C, Cavaletti G, Coan P. Establishing sample-preparation protocols for X-ray phase-contrast CT of rodent spinal cords: Aldehyde fixations and osmium impregnation. J Neurosci Methods. 2020 Jun 1;339:108744. doi: 10.1016/j.jneumeth.2020.108744. Epub 2020 Apr 27. PMID: 32353471.
Smith EML, Kuisell C, Kanzawa-Lee GA, Bridges CM, Alberti P, Cavaletti G, Saad R, Park S; Toxic Neuropathy Consortium of the Peripheral Nerve Society. Approaches to measure paediatric chemotherapy-induced peripheral neurotoxicity: a systematic review. Lancet Haematol. 2020 May;7(5):e408-e417. doi: 10.1016/S2352-3026(20)30064-8. PMID: 32359452; PMCID: PMC8152573.
Cavaletti G, Marmiroli P. Management of Oxaliplatin-Induced Peripheral Sensory Neuropathy. Cancers (Basel). 2020 May 27;12(6):1370. doi: 10.3390/cancers12061370. PMID: 32471028; PMCID: PMC7352541.
Listro R, Stotani S, Rossino G, Rui M, Malacrida A, Cavaletti G, Cortesi M, Arienti C, Tesei A, Rossi D, Giacomo MD, Miloso M, Collina S. Exploring the RC-106 Chemical Space: Design and Synthesis of Novel (E )-1-(3-Arylbut-2-en-1-yl)-4-(Substituted) Piperazine Derivatives as Potential Anticancer Agents. Front Chem. 2020 Jun 30;8:495. doi: 10.3389/fchem.2020.00495. PMID: 32695745; PMCID: PMC7338850.
Palmioli A, Ceresa C, Tripodi F, La Ferla B, Nicolini G, Airoldi C. On-cell saturation transfer difference NMR study of Bombesin binding to GRP receptor. Bioorg Chem. 2020 Jun;99:103861. doi: 10.1016/j.bioorg.2020.103861. Epub 2020 Apr 18. PMID: 32339813.
Bonomo R, Cavaletti G, Skene DJ. Metabolomics markers in Neurology: current knowledge and future perspectives for therapeutic targeting. Expert Rev Neurother. 2020 Jul;20(7):725-738. doi: 10.1080/14737175.2020.1782746. Epub 2020 Jun 27. PMID: 32538242.
Canta A, Chiorazzi A, Pozzi E, Fumagalli G, Monza L, Meregalli C, Carozzi VA, Rodriguez-Menendez V, Oggioni N, Näsström J, Marmiroli P, Cavaletti G. Calmangafodipir Reduces Sensory Alterations and Prevents Intraepidermal Nerve Fibers Loss in a Mouse Model of Oxaliplatin Induced Peripheral Neurotoxicity. Antioxidants (Basel). 2020 Jul 7;9(7):594. doi: 10.3390/antiox9070594. PMID: 32645985; PMCID: PMC7402145.
Liberatore G, Giannotta C, Sajeev BP, Morenghi E, Terenghi F, Gallia F, Doneddu PE, Manganelli F, Cocito D, Filosto M, Antonini G, Cosentino G, Marfia GA, Clerici AM, Lauria G, Rosso T, Cavaletti G, Nobile-Orazio E. Sensitivity and specificity of a commercial ELISA test for anti-MAG antibodies in patients with neuropathy. J Neuroimmunol. 2020 Aug 15;345:577288. doi: 10.1016/j.jneuroim.2020.577288. Epub 2020 Jun 8. PMID: 32544754.
Milani GP, Montomoli E; UNICORN Consortium investigators, Bollati V, Albetti B, Bandi C, Bellini T, Bonzini M, Buscaglia M, Cantarella C, Cantone L, Carugno M, Casartelli S, Cavaletti G, D’Alessandro S, De Chiara F, Delbue S, Dioni L, Eberini I, Favero C, Ferrari L, Ferraroni M, Galastri L, Galli C, Hoxha M, Iodice S, La Vecchia C, Macchi C, Manini I, Marchi S, Mariani J, Pariani E, Pesatori AC, Rota F, Ruscica M, Schioppo T, Tarantini L, Trombetta CM, Valsecchi MG, Vicenzi M, Zanchetta G. SARS-CoV-2 infection among asymptomatic homebound subjects in Milan, Italy. Eur J Intern Med. 2020 Aug;78:161-163. doi: 10.1016/j.ejim.2020.06.010. Epub 2020 Jun 9. PMID: 32564906; PMCID: PMC7280100.
Alberti P. Role of neurophysiology in Chemotherapy-Induced Peripheral Neuropathy (CIPN). Clin Neurophysiol. 2020 Aug;131(8):1964-1965. doi: 10.1016/j.clinph.2020.04.013. Epub 2020 May 1. PMID: 32417120.
Huang KM, Leblanc AF, Uddin ME, Kim JY, Chen M, Eisenmann ED, Gibson AA, Li Y, Hong KW, DiGiacomo D, Xia SH, Alberti P, Chiorazzi A, Housley SN, Cope TC, Sprowl JA, Wang J, Loprinzi CL, Noonan A, Lustberg MB, Cavaletti G, Pabla N, Hu S, Sparreboom A. Neuronal uptake transporters contribute to oxaliplatin neurotoxicity in mice . J Clin Invest. 2020 Sep 1;130(9):4601-4606. doi: 10.1172/JCI136796. PMID: 32484793; PMCID: PMC7456253.
Doneddu PE, Bianchi E, Cocito D, Manganelli F, Fazio R, Filosto M, Beghi E, Mazzeo A, Cosentino G, Cortese A, Jann S, Clerici AM, Antonini G, Siciliano G, Marfia GA, Briani C, Lauria G, Rosso T, Cavaletti G, Carpo M, Benedetti L, Schenone A, Liberatore G, Peci E, Spina E, Tronci S, Cotti Piccinelli S, Toscano A, Gentile L, Piccolo L, Leonardi L, Mataluni G, Ruiz M, Sabatelli M, Santoro L, Nobile-Orazio E; Italian CIDP Database Study Group. Impact of environmental factors and physical activity on disability and quality of life in CIDP. J Neurol. 2020 Sep;267(9):2683-2691. doi: 10.1007/s00415-020-09916-y. Epub 2020 May 19. PMID: 32430573.
Loprinzi CL, Lacchetti C, Bleeker J, Cavaletti G, Chauhan C, Hertz DL, Kelley MR, Lavino A, Lustberg MB, Paice JA, Schneider BP, Lavoie Smith EM, Smith ML, Smith TJ, Wagner-Johnston N, Hershman DL. Prevention and Management of Chemotherapy-Induced Peripheral Neuropathy in Survivors of Adult Cancers: ASCO Guideline Update. J Clin Oncol. 2020 Oct 1;38(28):3325-3348. doi: 10.1200/JCO.20.01399. Epub 2020 Jul 14. PMID: 32663120.
Argyriou AA, Bruna J, Park SB, Cavaletti G. Emerging pharmacological strategies for the management of chemotherapy-induced peripheral neurotoxicity (CIPN), based on novel CIPN mechanisms. Expert Rev Neurother. 2020 Oct;20(10):1005-1016. doi: 10.1080/14737175.2020.1796639. Epub 2020 Aug 6. PMID: 32667212.
Jordan B, Margulies A, Cardoso F, Cavaletti G, Haugnes HS, Jahn P, Le Rhun E, Preusser M, Scotté F, Taphoorn MJB, Jordan K; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org; EONS Education Working Group. Electronic address: eons.secretariat@cancernurse.eu; EANO Guideline Committee. Electronic address: office@eano.eu. Systemic anticancer therapy-induced peripheral and central neurotoxicity: ESMO-EONS-EANO Clinical Practice Guidelines for diagnosis, prevention, treatment and follow-up. Ann Oncol. 2020 Oct;31(10):1306-1319. doi: 10.1016/j.annonc.2020.07.003. Epub 2020 Jul 30. PMID: 32739407.
Magli S, Rossi GB, Risi G, Bertini S, Cosentino C, Crippa L, Ballarini E, Cavaletti G, Piazza L, Masseroni E, Nicotra F, Russo L. Design and Synthesis of Chitosan-Gelatin Hybrid Hydrogels for 3D Printable in vitro Models. Front Chem. 2020 Jul 14;8:524. doi: 10.3389/fchem.2020.00524. PMID: 32760695; PMCID: PMC7373092.
Doneddu PE, Cocito D, Manganelli F, Fazio R, Briani C, Filosto M, Benedetti L, Bianchi E, Jann S, Mazzeo A, Antonini G, Cosentino G, Marfia GA, Cortese A, Clerici AM, Carpo M, Schenone A, Siciliano G, Luigetti M, Lauria G, Rosso T, Cavaletti G, Beghi E, Liberatore G, Santoro L, Spina E, Peci E, Tronci S, Ruiz M, Cotti Piccinelli S, Verrengia EP, Gentile L, Leonardi L, Mataluni G, Piccolo L, Nobile-Orazio E; Italian CIDP Database study group. Frequency of diabetes and other comorbidities in chronic inflammatory demyelinating polyradiculoneuropathy and their impact on clinical presentation and response to therapy. J Neurol Neurosurg Psychiatry. 2020 Oct;91(10):1092-1099. doi: 10.1136/jnnp-2020-323615. Epub 2020 Aug 31. PMID: 32868387.
Canta A, Chiorazzi A, Pozzi E, Fumagalli G, Monza L, Meregalli C, Carozzi VA, Rodriguez-Menendez V, Oggioni N, Näsström J, Marmiroli P, Cavaletti G. Reply to a Comment Paper on the Published Paper by Canta, A. et al: “Calmangafodipir Reduces Sensory Alterations and Prevents Intraepidermal Nerve Fibers Loss in a Mouse Model of Oxaliplatin Induced Peripheral Neurotoxicity”-Antioxidants 2020, 9 , 594. Antioxidants (Basel). 2020 Sep 1;9(9):807. doi: 10.3390/antiox9090807. PMID: 32882796; PMCID: PMC7555122.
Pozzi E, Fumagalli G, Chiorazzi A, Canta A, Meregalli C, Monza L, Carozzi VA, Oggioni N, Rodriguez-Menendez V, Cavaletti G, Marmiroli P. The relevance of multimodal assessment in experimental oxaliplatin-induced peripheral neurotoxicity. Exp Neurol. 2020 Dec;334:113458. doi: 10.1016/j.expneurol.2020.113458. Epub 2020 Sep 2. PMID: 32889007.
Borgo F, Macandog AD, Diviccaro S, Falvo E, Giatti S, Cavaletti G, Melcangi RC. Alterations of gut microbiota composition in post-finasteride patients: a pilot study. J Endocrinol Invest. 2021 Jun;44(6):1263-1273. doi: 10.1007/s40618-020-01424-0. Epub 2020 Sep 19. PMID: 32951160; PMCID: PMC8124058.
Liberatore G, Manganelli F, Doneddu PE, Cocito D, Fazio R, Briani C, Filosto M, Benedetti L, Mazzeo A, Antonini G, Cosentino G, Jann S, Cortese A, Marfia GA, Clerici AM, Siciliano G, Carpo M, Luigetti M, Lauria G, Rosso T, Cavaletti G, Santoro L, Peci E, Tronci S, Ruiz M, Cotti Piccinelli S, Schenone A, Leonardi L, Toscano A, Mataluni G, Spina E, Gentile L, Nobile-Orazio E; Italian CIDP Database Study Group. Chronic inflammatory demyelinating polyradiculoneuropathy: can a diagnosis be made in patients not fulfilling electrodiagnostic criteria? Eur J Neurol. 2021 Feb;28(2):620-629. doi: 10.1111/ene.14545. Epub 2020 Oct 15. PMID: 32959475.
Dionisi M, Ruffinatti FA, Riva B, Lim D, Canta A, Meregalli C, Fumagalli G, Monza L, Ferrer-Montiel A, Fernandez-Carvajal A, Cavaletti G, Genazzani AA, Distasi C. Early Stimulation of TREK Channel Transcription and Activity Induced by Oxaliplatin-Dependent Cytosolic Acidification. Int J Mol Sci. 2020 Sep 28;21(19):7164. doi: 10.3390/ijms21197164. PMID: 32998392; PMCID: PMC7584002.
Lepore V, Bosetti C, Santucci C, Iaffaldano P, Trojano M, Mosconi P; Italian Multiple Sclerosis Register Centers Group, the Scientific Committee of Italian SM Register. Detection of disability worsening in relapsing-remitting multiple sclerosis patients: a real-world roving Expanded Disability Status Scale reference analysis from the Italian Multiple Sclerosis Register. Eur J Neurol. 2021 Feb;28(2):567-578. doi: 10.1111/ene.14589. Epub 2020 Nov 6. PMID: 33058344.
Barbone GE, Bravin A, Mittone A, Grosu S, Ricke J, Cavaletti G, Djonov V, Coan P. High-Spatial-Resolution Three-dimensional Imaging of Human Spinal Cord and Column Anatomy with Postmortem X-ray Phase-Contrast Micro-CT. Radiology. 2021 Jan;298(1):135-146. doi: 10.1148/radiol.2020201622. Epub 2020 Oct 27. PMID: 33107800.
Fontana D, Mauri M, Renso R, Docci M, Crespiatico I, Røst LM, Jang M, Niro A, D’Aliberti D, Massimino L, Bertagna M, Zambrotta G, Bossi M, Citterio S, Crescenzi B, Fanelli F, Cassina V, Corti R, Salerno D, Nardo L, Chinello C, Mantegazza F, Mecucci C, Magni F, Cavaletti G, Bruheim P, Rea D, Larsen S, Gambacorti-Passerini C, Piazza R. ETNK1 mutations induce a mutator phenotype that can be reverted with phosphoethanolamine. Nat Commun. 2020 Nov 23;11(1):5938. doi: 10.1038/s41467-020-19721-w. PMID: 33230096; PMCID: PMC7684297.
Alberti P. A review of novel biomarkers and imaging techniques for assessing the severity of chemotherapy-induced peripheral neuropathy. Expert Opin Drug Metab Toxicol. 2020 Dec;16(12):1147-1158. doi: 10.1080/17425255.2021.1842873. Epub 2020 Nov 8. PMID: 33103947.
2019
Alberti P, Cavaletti G, Cornblath DR. Toxic neuropathies: Chemotherapy Induced Peripheral Neurotoxicity. Curr Opin Neurol. 2019 Oct;32(5):676-683. doi: 10.1097/WCO.0000000000000724. PubMed PMID: 31306214
Alberti P. Platinum-drugs induced peripheral neurotoxicity: clinical course and preclinical evidence. Expert Opin Drug Metab Toxicol. 2019 Jun;15(6):487-497. doi: 10.1080/17425255.2019.1622679. PubMed PMID: 31116618
Argyriou AA, Antonacopoulou AG, Alberti P, Briani C, Bruna J, Velasco R, Anastopoulou GG, Park SB, Cavaletti G, Kalofonos HP. Liability of the voltage-gated potassium channel KCNN3 repeat polymorphism to acute oxaliplatin-induced peripheral neurotoxicity. J Peripher Nerv Syst. 2019 Dec;24(4):298-303. doi: 10.1111/jns.12347. Epub 2019 Oct 16. PubMed [citation] PMID: 31486252
Argyriou AA, Cavaletti G, Park SB; Toxic Neuropathy Consortium (TNC). The Toxic Neuropathy Consortium of the Peripheral Nerve Society. J Peripher Nerv Syst. 2019 Oct;24 Suppl 2:S4-S5. doi: 10.1111/jns.12331. PubMed PMID: 31647150.
Argyriou AA, Park SB, Bruna J, Cavaletti G. Voltage-gated sodium channel dysfunction and the search for other satellite channels in relation to acute oxaliplatin-induced peripheral neurotoxicity . J Peripher Nerv Syst. 2019 Dec;24(4):360-361. doi: 10.1111/jns.12354. Epub 2019 Nov 7. PubMed PMID: 31696990.
Argyriou AA, Park SB, Islam B, Tamburin S, Velasco R, Alberti P, Bruna J, Psimaras D, Cavaletti G, Cornblath DR; Toxic Neuropathy Consortium (TNC). Neurophysiological, nerve imaging and other techniques to assess chemotherapy-induced peripheral neurotoxicity in the clinical and research settings. J Neurol Neurosurg Psychiatry. 2019 Dec;90(12):1361-1369. doi: 10.1136/jnnp-2019-320969. Review. PubMed PMID: 31256000
Arosio A, Cristofani R, Pansarasa O, Crippa V, Riva C, Sirtori R, Rodriguez-Menendez V, Riva N, Gerardi F, Lunetta C, Cereda C, Poletti A, Ferrarese C, Tremolizzo L, Sala G. HSC70 expression is reduced in lymphomonocytes of sporadic ALS patients and contributes to TDP-43 accumulation.
Calls A*, Carozzi V*, Navarro X, Monza L, Bruna J. Pathogenesis of platinum-induced peripheral neurotoxicity: Insights from preclinical studies
Cavaletti G, Alberti P, Argyriou AA, Lustberg M, Staff NP, Tamburin S; Toxic Neuropathy Consortium of the Peripheral Nerve Society. Chemotherapy-induced peripheral neurotoxicity: A multifaceted, still unsolved issue . J Peripher Nerv Syst. 2019 Oct;24 Suppl 2:S6-S12. doi: 10.1111/jns.12337. Review. PubMed [citation] PMID: 31647155
Cavaletti G, Cornblath DR, Merkies ISJ, Postma TJ, Rossi E, Alberti P, Bruna J, Argyriou AA, Briani C, Velasco R, Kalofonos HP, Psimaras D, Ricard D, Pace A, Faber CG, Lalisang RI, Brandsma D, Koeppen S, Kerrigan S, Schenone A, Grisold W, Mazzeo A, et al. Patients’ and physicians’ interpretation of chemotherapy-induced peripheral neurotoxicity. J Peripher Nerv Syst. 2019 Mar;24(1):111-119. doi: 10.1111/jns.12306. Epub 2019 Feb 8. PubMed PMID: 30672664
Cavaletti G, Cornblath DR. Chemotherapy-induced peripheral neurotoxicity: Facts, needs and future directions. J Peripher Nerv Syst. 2019 Oct;24 Suppl 2:S86-S87. doi: 10.1111/jns.12332. PubMed PMID: 31647156.
Di Lorenzo F, Alberti P, Pavolucci L, Pietrafusa N, Iodice F. Introduction to the Italian section for young neurologists. Neurol Sci. 2019 Nov;40(11):2423-2424. doi: 10.1007/s10072-019-03967-4. Epub 2019 Jun 14. No abstract available. PubMed PMID: 31201599
Doneddu PE, Cocito D, Manganelli F, Fazio R, Briani C, Filosto M, Benedetti L, Mazzeo A, Marfia GA, Cortese A, Fierro B, Jann S, Beghi E, Clerici AM, Carpo M, Schenone A, Luigetti M, Lauria G, Antonini G, Rosso T, Siciliano G, Cavaletti G, Liberatore G, Santoro L, Peci E, Tronci S, Ruiz M, Cotti Piccinelli S, Toscano A, Mataluni G, Piccolo L, Cosentino G, Sabatelli M, Nobile-Orazio E; Italian CIDP Database study group. Atypical CIDP: diagnostic criteria, progression and treatment response. Data from the Italian CIDP Database . J Neurol Neurosurg Psychiatry. 2019 Feb;90(2):125-132. doi: 10.1136/jnnp-2018-318714. PubMed PMID: 30297520.
Dorsey SG, Kleckner IR, Barton D, Mustian K, O’Mara A, St Germain D, Cavaletti G, Danhauer SC, Hershman D, Hohmann AG, Hoke A, Hopkins JO, Kelly KP, Loprinzi CL, McLeod HL, Mohile S, Paice J, Rowland JH, Salvemini D, Segal RA, Lavoie Smith E, McCaskill Stevens W, Janelsins MC. NCI Clinical Trials Planning Meeting for prevention and treatment of chemotherapy-induced peripheral neuropathy. J Natl Cancer Inst. 2019 Jun 1;111(6):531-537. doi: 10.1093/jnci/djz011. PMID: 30715378.
Farina F, Lonati E, Milani C, Massimino L, Ballarini E, Donzelli E, Crippa L, Marmiroli P, Botto L, Corsetto PA, Sancini G, Bulbarelli A, Palestini P.In Vivo Comparative Study on Acute and Sub-acute Biological Effects Induced by Ultrafine Particles of Different Anthropogenic Sources in BALB/c Mice.
Formicola B, D’Aloia A, Dal Magro Ra, Stucchi S, Rigolio R, Ceriani M, Re F. Differential Exchange of Multifunctional Liposomes Between Glioblastoma Cells and Healthy Astrocytes via Tunneling Nanotubes.
Gewandter JS, Gibbons CH, Campagnolo M, Lee J, Chaudari J, Ward N, Burke L, Cavaletti G, Herrmann DN, McArthur JC, Russell JW, Smith AG, Smith SM, Turk DC, Dworkin RH, Freeman R. Clinician-rated measures for distal symmetrical axonal polyneuropathy: ACTTION systematic review. Neurology. 2019 Aug 20;93(8):346-360. doi: 10.1212/WNL.0000000000007974. Epub 2019 Jul 18. Review. PubMed PMID: 31320471.
Hucke A, Rinschen MM, Bauer OB, Sperling M, Karst U, Köppen C, Sommer K, Schröter R, Ceresa C, Chiorazzi A, Canta A, Semperboni S, Marmiroli P, Cavaletti G, Schlatt S, Schlatter E, Pavenstädt H, Heitplatz B, Van Marck V, Sparreboom A, Barz V, Knief A, Deuster D, Zehnhoff-Dinnesen AA, Ciarimboli G.An integrative approach to cisplatin chronic toxicities in mice reveals importance of organic cation-transporter-dependent protein networks for renoprotection.
Islam B, Lustberg M, Staff NP, Kolb N, Alberti P, Argyriou AA. Vinca alkaloids, thalidomide and eribulin-induced peripheral neurotoxicity: From pathogenesis to treatment. J Peripher Nerv Syst. 2019 Oct;24 Suppl 2:S63-S73. doi: 10.1111/jns.12334. Review. PubMed [citation] PMID: 31647152
Lessans S, Lassiter CB, Carozzi V, Heindel P, Semperboni S, Oggioni N, Chiorazzi A, Thompson C, Wagner M, Holden J, Rahn E, Sweatt JD, Cavaletti G, Renn CL, Dorsey SG. Global Transcriptomic Profile of Dorsal Root Ganglion and Physiological Correlates of Cisplatin-Induced Peripheral Neuropathy.
Malacrida A, Cavalloro V, Martino E, Cassetti A, Nicolini G, Rigolio R, Cavaletti G, Mannucci B, Vasile F, Giacomo MD, Collina S, Miloso M. Anti-Multiple Myeloma Potential of Secondary Metabolites from Hibiscus sabdariffa. Chemotherapy-Induced Peripheral Neuropathy and Changes in Cytoskeleton
Malacrida A, Rivara M, Di Domizio A, Cislaghi G, Miloso M, Zuliani V, Nicolini G. (2019) 3D proteome-wide scale screening and activity evaluation of a new ALKBH5 inhibitor in U87 glioblastoma cell line.
Mariotto S, Tecchio C, Sorio M, Bertolasi L, Turatti M, Tozzi MC, Benedetti F, Cavaletti G, Monaco S, Ferrari S. Clinical and neurophysiological serial assessments of brentuximab vedotin-associated peripheral neuropathy. Leuk Lymphoma. 2019 Nov;60(11):2806-2809. doi: 10.1080/10428194.2019.1605068. PubMed PMID: 31057013.
Melcangi RC, Casarini L, Marino M, Santi D, Sperduti S, Giatti S, Diviccaro S, Grimoldi M, Caruso D, Cavaletti G, Simoni M. Altered methylation pattern of the SRD5A2 gene in the cerebrospinal fluid of post-finasteride patients: a pilot study. Endocr Connect. 2019 Aug 1;8(8):1118-1125. doi: 10.1530/EC-19-0199. PubMed PMID: 31272082; PubMed Central PMCID: PMC6652249.
Murtaj V, Belloli S, Di Grigoli G, Pannese M, Ballarini E, Rodriguez-Menendez V, Marmiroli P, Cappelli A, Masiello V, Monterisi C, Bellelli G, Panina-Bordignon P, Moresco RM.Age and Sex Influence the Neuro-inflammatory Response to a Peripheral Acute LPS Challenge.
Park SB, Alberti P, Kolb NA, Gewandter JS, Schenone A, Argyriou AA. Overview and critical revision of clinical assessment tools in chemotherapy-induced peripheral neurotoxicity. J Peripher Nerv Syst. 2019 Oct;24 Suppl 2:S13-S25. doi: 10.1111/jns.12333. Review. PubMed PMID: 31647154
Potenzieri A, Riva B, Rigolio R, Chiorazzi A, Pozzi E, Ballarini E, Cavaletti G, Genazzani AA. Oxaliplatin-induced neuropathy occurs through impairment of haemoglobin proton buffering and is reversed by carbonic anhydrase inhibitors.
Scarpazza C, Signori A, Prosperini L, Sormani MP, Cosottini M, Capra R, Gerevini S; Italian PML Group. Early diagnosis of progressive multifocal leucoencephalopathy: longitudinal lesion evolution. J Neurol Neurosurg Psychiatry. 2019 Mar;90(3):261-267. doi: 10.1136/jnnp-2018-319208. PubMed PMID: 30389778.
Smith EML, Banerjee T, Yang JJ, Bridges CM, Alberti P, Sloan JA, Loprinzi C. Psychometric Testing of the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Chemotherapy-Induced Peripheral Neuropathy 20-Item Scale Using Pooled Chemotherapy-Induced Peripheral Neuropathy Outcome Measures Standardization and Alliance for Clinical Trials in Oncology A151408 Study Data. Cancer Nurs. 2019 May/Jun;42(3):179-189. doi: 10.1097/NCC.0000000000000596. PubMed PMID: 29649081, PMCID: PMC6185825
Staff NP, Cavaletti G, Islam B, Lustberg M, Psimaras D, Tamburin S. Platinum-induced peripheral neurotoxicity: From pathogenesis to treatment. J Peripher Nerv Syst. 2019 Oct;24 Suppl 2:S26-S39. doi: 10.1111/jns.12335. Review. PubMed PMID: 31647151; PubMed Central PMCID: PMC6818741.
Tamburin S, Park SB, Alberti P, Demichelis C, Schenone A, Argyriou AA. Taxane and epothilone-induced peripheral neurotoxicity: From pathogenesis to treatment. J Peripher Nerv Syst. 2019 Oct;24 Suppl 2:S40-S51. doi: 10.1111/jns.12336. Review. PubMed PMID: 31647157
Tesei A, Cortesi M, Pignatta S, Arienti C, Dondio GM, Bigogno C, Malacrida A, Miloso M, Meregalli C, Chiorazzi A, Carozzi V, Cavaletti G, Rui M, Marra A, Rossi D, Collina S. (2019) Anti-tumor Efficacy Assessment of the Sigma Receptor Pan Modulator RC-106. A Promising Therapeutic Tool for Pancreatic Cancer.
Trojano M, Bergamaschi R, Amato MP, Comi G, Ghezzi A, Lepore V, Marrosu MG, Mosconi P, Patti F, Ponzio M, Zaratin P, Battaglia MA; Italian Multiple Sclerosis Register Centers Group. The Italian multiple sclerosis register. Neurol Sci. 2019 Jan;40(1):155-165. doi: 10.1007/s10072-018-3610-0. Epub 2018 Nov 13. Erratum in: Neurol Sci. 2019 Apr;40(4):907. PubMed PMID: 30426289; PubMed Central PMCID: PMC6329744.
Velasco R, Alberti P, Bruna J, Psimaras D, Argyriou AA. Bortezomib and other proteosome inhibitors-induced peripheral neurotoxicity: From pathogenesis to treatment. J Peripher Nerv Syst. 2019 Oct;24 Suppl 2:S52-S62. doi: 10.1111/jns.12338. Review. PubMed PMID: 31647153
Verboon C, Doets AY, Galassi G, Davidson A, Waheed W, Péréon Y, Shahrizaila N, Kusunoki S, Lehmann HC, Harbo T, Monges S, Van den Bergh P, Willison HJ, Cornblath DR, Jacobs BC; IGOS Consortium. Current treatment practice of Guillain-Barré syndrome. Neurology. 2019 Jul 2;93(1):e59-e76. doi: 10.1212/WNL.0000000000007719. Epub 2019 Jun 7. PubMed PMID: 31175208.
2018
Chiorazzi A, Wozniak KM, Raisb R, Wu Y, Gadiano AG, Farah MH, Liu Y, Canta A, Alberti P, Rodriguez-Menendez V, Meregalli C, Fumagalli G, Monza L, Pozzi E, Vornov JJ, Polydefkis M, Pietra C, Slusher BS, Cavaletti G. Ghrelin Agonist HM01 Attenuates Chemotherapy- Induced Neurotoxicity in Rodent Models. Eur J Pharmacol. 2018 Dec 5;840:89-103. doi: 10.1016/j.ejphar.2018.09.029. Epub 2018 Sep 27.
Scarpazza, C., Signori, A., Prosperini, L., Sormani, M.P., Cosottini, M., Capra, R., Gerevini, S., Altieri, M., Amato, M.P., Artusi, C.A., Bandini, F., Barcella, V., Bertolotto, A., Morra, V.B., Capobianco, M., Cavaletti, G., Cavalla, P., Centonze, D., Chiusole, M., Clerico, M., Cordioli, C., D’Aleo, G., De Luca, G., De Riz, M., De Rossi, N., Deotto, L., Durelli, L., Falcini, M., Ferrante, C., Ferrari, E., Fusco, M.L., Gasperini, C., Ghezzi, A., Grimaldi, L., Guidotti, M., Laroni, A., Lugaresi, A., Moiola, L., Naldi, P., Pane, C., Palmeri, B., Perrone, P., Pizzorno, M., Pozzilli, C., Rezzonico, M., Rottoli, M.R., Rovaris, M., Salemi, G., Salvetti, M., Santuccio, G., Scarpini, E., Sessa, E., Solaro, C., Stenta, G., Tabiadon, G., Tortorella, C., Trojano, M., Valentino, P., Rottoli, M.R., the Italian PML Group. Early diagnosis of progressive multifocal leucoencephalopathy: Longitudinal lesion evolution . J Neurol Neurosurg Psychiatry. 2018 Nov 2. pii: jnnp-2018-319208. doi: 10.1136/jnnp-2018-319208. [Epub ahead of print]
Rui M, Rossino G, Coniglio S, Monteleone S, Scuteri A., Malacrida A, Rossi D, Catenacci L, Sorrenti M, Paolillo M, Curti D, Venturini L, Schepmann D, Wünsch B,Liedl KR, Cavaletti G, Pace V, Urban E, Collina S. Identification of dual Sigma1 receptor modulators/acetylcholinesterase inhibitors with antioxidant and neurotrophic properties, as neuroprotective agents. Eur J Med Chem. 2018 Oct 5;158:353-370. doi: 10.1016/j.ejmech.2018.09.010.
Riva, B., Dionisi, M., Potenzieri, A., Chiorazzi, A., Cordero-Sanchez, C., Rigolio, R., Carozzi, V.A., Lim, D., Cavaletti, G., Marmiroli, P., Distasi, C., Genazzani, A.A. Oxaliplatin induces pH acidification in dorsal root ganglia neurons . Sci Rep. 2018 Oct 10;8(1):15084. doi: 10.1038/s41598-018-33508-6.
Doets, A.Y., Verboon, C., Van Den Berg, B., Harbo, T., Cornblath, D.R., Willison, H.J., Islam, Z., Attarian, S., Barroso, F.A., Bateman, K., Benedetti, L., Van Den Bergh, P., Casasnovas, C., Cavaletti, G., Chavada, G., Claeys, K.G., Dardiotis, E., Davidson, A., Van Doorn, P.A., Feasby, T.E., Galassi, G., Gorson, K.C., Hartung, H.-P., Hsieh, S.-T., Hughes, R.A.C., Illa, I., Islam, B., Kusunoki, S., Kuwabara, S., Lehmann, H.C., Miller, J.A.L., Mohammad, Q.D., Monges, S., Nobile Orazio, E., Pardo, J., Pereon, Y., Rinaldi, S., Querol, L., Reddel, S.W., Reisin, R.C., Shahrizaila, N., Sindrup, S.H., Waqar, W., Jacobs, B.C. Regional variation of Guillain-Barré syndrome. Brain. 2018 Oct 1;141(10):2866-2877. doi: 10.1093/brain/awy232.
Ambrosini, A., Calabrese, D., Avato, F.M., Catania, F., Cavaletti, G., Pera, M.C., Toscano, A., Vita, G., Monaco, L., Pareyson, D. The Italian neuromuscular registry: A coordinated platform where patient organizations and clinicians collaborate for data collection and multiple usage. Orphanet J Rare Dis. 2018 Oct 4;13(1):176. doi: 10.1186/s13023-018-0918-z.
Scuteri A., Monfrini M. Mesenchymal Stem Cells as New Therapeutic Approach for Diabetes and Pancreatic Disorders. Int J Mol Sci. 2018 Sep 16;19(9). pii: E2783. doi: 10.3390/ijms19092783.
Meregalli C, Fumagalli G, Alberti P, Canta A, Carozzi VA, Chiorazzi A, Monza L, Pozzi E, Sandelius Å, Blennow K, Zetterberg H, Marmiroli P, Cavaletti G. Neurofilament light chain as disease biomarker in a rodent model of chemotherapy induced peripheral neuropathy. Exp Neurol. 2018 Sep;307:129-132.
Alberti P, Rossi E, Argyriou AA, Kalofonos HP, Briani C, Cacciavillani M, Campagnolo M, Bruna J, Velasco R, Cazzaniga ME, Cortinovis D, Valsecchi MG, Cavaletti G. Risk stratification of oxaliplatin induced peripheral neurotoxicity applying electrophysiological testing of dorsal sural nerve. Support Care Cancer. 2018 Sep;26(9):3143-3151. doi: 10.1007/s00520-018-4170-9. Epub 2018 Mar 29.
Meregalli C, Marjanovic I, Scali C, Monza L, Spinoni N, Galliani C, Brivio R, Chiorazzi A, Ballarini E, Rodriguez-Menendez V, Carozzi VA, Alberti P, Fumagalli G, Pozzi E, Canta A, Quartu M, Briani C, Marmiroli P, Cavaletti G. High-Dose Intravenous Immunoglobulins Reduce Nerve Macrophages Infiltration and the Severity of Bortezomib-Induced Peripheral Neurotoxicity in Rats. J Neuroinflammation. 2018 Aug 21;15(1):232.
Gewandter, J.S., Brell, J., Cavaletti, G., Dougherty, P.M., Evans, S., Howie, L., McDermott, M.P., O’Mara, A., Gordon Smith, A., Dastros-Pitei, D., Gauthier, L.R., Haroutounian, S., Jarpe, M., Katz, N.P., Loprinzi, C., Richardson, P., Lavoie-Smith, E.M., Wen, P.Y., Turk, D.C., Dworkin, R.H., Freeman, R. Trial designs for chemotherapy-induced peripheral neuropathy prevention . Neurology. 2018 Aug 28;91(9):403-413. doi: 10.1212/WNL.0000000000006083. Epub 2018 Jul 27.
Ceresa C, Nicolini G, Semperboni S, Gandin V, Monfrini M, Avezza F, Alberti P, Bravin A, Pellei M, Santini C, Cavaletti G. Evaluation of the Profile and Mechanism of Neurotoxicity of Water-Soluble [Cu(P)4]PF6 and [Au(P)4]PF6 (P = thp or PTA) Anticancer Complexes. Neurotox Res. 2018 Jul;34(1):93-108. doi: 10.1007/s12640-018-9864-8. Epub 2018 Jan 17.
van Leeuwen M, Husson O, Alberti P, Arraras JI, Chinot OL, Costantini A, Darlington AS, Dirven L, Eichler M, Hammerlid EB, Holzner B, Johnson CD, Kontogianni M, Kjær TK, Morag O, Nolte S, Nordin A, Pace A, Pinto M, Polz K, Ramage J, Reijneveld JC, Serpentini S, Tomaszewski KA, Vassiliou V, Verdonck-de Leeuw IM, Vistad I, Young TE, Aaronson NK, van de Poll-Franse LV. Understanding the quality of life (QOL) issues in survivors of cancer: towards the development of an EORTC QOL cancer survivorship questionnaire. Health Qual Life Outcomes. 2018 Jun 4;16(1):114. doi: 10.1186/s12955-018-0920-0.
Smith EML, Banerjee T, Yang JJ, Bridges CM, Alberti P, Sloan JA, Loprinzi C. Psychometric Testing of the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Chemotherapy-Induced Peripheral Neuropathy 20-Item Scale Using Pooled Chemotherapy-Induced Peripheral Neuropathy Outcome Measures Standardization and Alliance for Clinical Trials in Oncology A151408 Study Data. Cancer Nurs. 2018 Apr 12. doi: 10.1097/NCC.0000000000000596.
Van Helleputte, L., Kater, M., Cook, D.P., Eykens, C., Rossaert, E., Haeck, W., Jaspers, T., Geens, N., Vanden Berghe, P., Gysemans, C., Mathieu, C., Robberecht, W., Van Damme, P., Cavaletti, G., Jarpe, M., Van Den Bosch, L. Inhibition of histone deacetylase 6 (HDAC6) protects against vincristine-induced peripheral neuropathies and inhibits tumor growth. Neurobiol Dis. 2018 Mar;111:59-69. doi: 10.1016/j.nbd.2017.11.011. Epub 2017 Nov 29.
Cavaletti, G., Marmiroli, P. Pharmacotherapy options for managing chemotherapy-induced peripheral neurotoxicity. Expert Opin Pharmacother. 2018 Feb;19(2):113-121. doi: 10.1080/14656566.2017.1415326. Epub 2017 Dec 15.
Wozniak KM, Vornov JJ, Wu Y, Liu Y, Carozzi VA, Rodriguez-Menendez V, Ballarini E, Alberti P, Pozzi E, Semperboni S, Cook BM, Littlefield BA, Nomoto K, Condon K, Eckley S, DesJardins C, Wilson L, Jordan MA, Feinstein SC, Cavaletti G, Polydefkis M, Slusher BS. Peripheral Neuropathy Induced by Microtubule-Targeted Chemotherapies: Insights into Acute Injury and Long-term Recovery. Cancer Res. 2018 Feb 1;78(3):817-829. doi: 10.1158/0008-5472.CAN-17-1467. Epub 2017 Nov 30.
Dal Magro R, Albertini B, Beretta S, Rigolio R, Donzelli E, Chiorazzi A, Ricci M, Blasi P, Sancini G. Artificial apolipoprotein corona enables nanoparticle brain targeting. Nanomedicine. 2018 Feb 21;14(2):429-438. doi: 10.1016/j.nano.2017.11.008.
Leblanc AF, Sprowl JA, Alberti P, Chiorazzi A, Arnold WD, Gibson AA, Hong KW, Pioso MS, Chen M, Huang KM, Chodisetty V, Costa O, Florea T, de Bruijn P, Mathijssen RH, Reinbolt RE, Lustberg MB, Sucheston-Campbell LE, Cavaletti G, Sparreboom A, Hu S.OATP1B2 deficiency protects against paclitaxel-induced neurotoxicity. J Clin Invest. 2018 Feb 1;128(2):816-825. doi: 10.1172/JCI96160. Epub 2018 Jan 16.
Bruna J, Videla S, Argyriou AA, Velasco R, Villoria J, Santos C, Nadal C, Cavaletti G, Alberti P, Briani C, Kalofonos HP, Cortinovis D, Sust M, Vaqué A, Klein T, Plata-Salamán C. Efficacy of a Novel Sigma-1 Receptor Antagonist for Oxaliplatin-Induced Neuropathy: A Randomized, Double-Blind, Placebo-Controlled Phase IIa Clinical Trial. Neurotherapeutics. 2018 Jan;15(1):178-189. doi: 10.1007/s13311-017-0572-5..
Monfrini M, Ravasi M, Maggioni D, Donzelli E, Tredici G, Cavaletti G, Scuteri A. Comparing the different response of PNS and CNS injured neurons to mesenchymal stem cell treatment. Mol Cell Neurosci. 2018 Jan;86:16-24. doi: 10.1016/j.mcn.2017.11.004. Epub 2017 Nov 6.
2017
Alberti P. Chemotherapy-induced peripheral neurotoxicity – outcome measures: the issue. Expert Opin Drug Metab Toxicol. 2017 Mar;13(3):241-243. doi: 10.1080/17425255.2017.1258400.
Argyriou AA, Bruna J, Genazzani AA, Cavaletti G. Chemotherapy-induced peripheral neurotoxicity: management informed by pharmacogenetics. Nat Rev Neurol. 2017 Aug;13(8):492-504. doi: 10.1038/nrneurol.2017.88.
Avallone G, Pellegrino V, Roccabianca P, Lepri E, Crippa L, Beha G, De Tolla L, Sarli G. Tyrosine Kinase Receptor Expression in Canine Liposarcoma . Vet Pathol. 2017 Mar;54(2):212-217. doi: 10.1177/0300985816671379.
Beretta S, Versace A, Carone D, Riva M, Dell’Era V, Cuccione E, Cai R, Monza L, Pirovano S, Padovano G, Stiro F, Presotto L, Paternò G, Rossi E, Giussani C, Sganzerla EP, Ferrarese C. Cerebral collateral therapeutics in acute ischemic stroke: A randomized preclinical trial of four modulation strategies. J Cereb Blood Flow Metab. 2017 Oct;37(10):3344-3354. doi: 10.1177/0271678X16688705.
Bruna J, Videla S, Argyriou AA, Velasco R, Villoria J, Santos C, Nadal C, Cavaletti G, Alberti P, Briani C, Kalofonos HP, Cortinovis D, Sust M, Vaqué A, Klein T, Plata-Salamán C. Efficacy of a Novel Sigma-1 Receptor Antagonist for Oxaliplatin-Induced Neuropathy: A Randomized, Double-Blind, Placebo-Controlled Phase IIa Clinical Trial. Neurotherapeutics. 2017 Sep 18. doi: 10.1007/s13311-017-0572-5.
Carrà G, Nicolini G, Lax A, Bartoli F, Castellano F, Chiorazzi A, Gamba G, Bava M, Crocamo C, Papagno C. Facial emotion recognition in schizophrenia: An exploratory study on the role of comorbid alcohol and substance use disorders and COMT Val158Met. Hum Psychopharmacol. 2017 Nov;32(6). doi: 10.1002/hup.2630. Epub 2017 Sep 15
Cavaletti G, Marmiroli P. Pharmacotherapy options for managing chemotherapy-induced peripheral neurotoxicity. Expert Opin Pharmacother. 2017 Dec 15:1-9. doi: 10.1080/14656566.2017.1415326.
Collina S, Rui M, Stotani S, Bignardi E, Rossi D, Curti D, Giordanetto F, Malacrida A, Scuteri A, Cavaletti G. Are sigma receptor modulators a weapon against multiple sclerosis disease? Future Med Chem. 2017 Nov;9(17):2029-2051. doi: 10.4155/fmc-2017-0122.
Cuccione E, Versace A, Cho TH, Carone D, Berner LP, Ong E, Rousseau D, Cai R, Monza L, Ferrarese C, Sganzerla EP, Berthezène Y, Nighoghossian N, Wiart M, Beretta S, Chauveau F. Multi-site laser Doppler flowmetry for assessing collateral flow in experimental ischemic stroke: Validation of outcome prediction with acute MRI. J Cereb Blood Flow Metab. 2017 Jun;37(6):2159-2170. doi: 10.1177/0271678X16661567.
Dal Magro R, Ornaghi F, Cambianica I, Beretta S, Re F, Musicanti C, Rigolio R, Donzelli E, Canta A, Ballarini E, Cavaletti G, Gasco P, Sancini G. ApoE-modified solid lipid nanoparticles: A feasible strategy to cross the blood-brain barrier. J Control Release. 2017 Mar 10;249:103-110. doi: 10.1016/j.jconrel.2017.01.039.
Gandin V, Ceresa C, Esposito G, Indraccolo S, Porchia M, Tisato F, Santini C, Pellei M, Marzano C. Therapeutic potential of the phosphino Cu(I) complex (HydroCuP) in the treatment of solid tumors. Sci Rep. 2017 Oct 24;7(1):13936. doi: 10.1038/s41598-017-13698-1.
Gastaldi M, Zardini E, Leante R, Ruggieri M, Costa G, Cocco E, De Luca G, Cataldo I, Biagioli T, Ballerini C, Castellazzi M, Fainardi E, Pettini P, Zaffaroni M, Giunti D, Capello E, Bernardi G, Ciusani E, Giannotta C, Nobile-Orazio E, Bazzigaluppi E, Passerini G, Bedin R, Sola P, Brivio R, Cavaletti G, Sala A, Bertolotto A, Desina G, Leone MA, Mariotto S, Ferrari S, Paternoster A, Giavarina D, Lolli F, Franciotta D. Cerebrospinal fluid analysis and the determination of oligoclonal bands. Neurol Sci. 2017 Oct;38(Suppl 2):217-224. doi: 10.1007/s10072-017-3034-2.
Gewandter JS, Burke L, Cavaletti G, Dworkin RH, Gibbons C, Gover TD, Herrmann DN, Mcarthur JC, McDermott MP, Rappaport BA, Reeve BB, Russell JW, Smith AG, Smith SM, Turk DC, Vinik AI, Freeman R. Content validity of symptom-based measures for diabetic, chemotherapy, and HIV peripheral neuropathy. Muscle Nerve. 2017 Mar;55(3):366-372. doi: 10.1002/mus.25264.
Gewandter JS, Freeman R, Kitt RA, Cavaletti G, Gauthier LR, McDermott MP, Mohile NA, Mohlie SG, Smith AG, Tejani MA, Turk DC, Dworkin RH. Chemotherapy-induced peripheral neuropathy clinical trials: Review and recommendations. Neurology. 2017 Aug 22;89(8):859-869. doi: 10.1212/WNL.0000000000004272.
Griffith KA, Zhu S, Johantgen M, Kessler MD, Renn C, Beutler AS, Kanwar R, Ambulos N, Cavaletti G, Bruna J, Briani C, Argyriou AA, Kalofonos HP, Yerges-Armstrong LM, Dorsey SG. Oxaliplatin-Induced Peripheral Neuropathy and Identification of Unique Severity Groups in Colorectal Cancer. J Pain Symptom Manage. 2017 Nov;54(5):701-706.e1. doi: 10.1016/j.jpainsymman.2017.07.033.
Kieffer JM, Postma TJ, van de Poll-Franse L, Mols F, Heimans JJ, Cavaletti G, Aaronson NK; CI-PeriNomS Group. Evaluation of the psychometric properties of the EORTC chemotherapy-induced peripheral neuropathy questionnaire (QLQ-CIPN20). Qual Life Res. 2017 Nov;26(11):2999-3010. doi: 10.1007/s11136-017-1626-1.
Lavoie Smith EM, Haupt R, Kelly JP, Lee D, Kanzawa-Lee G, Knoerl R, Bridges C, Alberti P, Prasertsri N, Donohoe C. The Content Validity of a Chemotherapy-Induced Peripheral Neuropathy Patient-Reported Outcome Measure. Oncol Nurs Forum. 2017 Sep 1;44(5):580-588. doi: 10.1188/17.ONF.580-588.
Manodoro S, Spelzini F, Cesana MC, Frigerio M, Maggioni D, Ceresa C, Penati C, Sicuri M, Fruscio R, Nicolini G, Milani R. Histologic and metabolic assessment in a cohort of patients with genital prolapse: preoperative stage and recurrence investigations. Minerva Ginecol. 2017 Jun;69(3):233-238. doi: 10.23736/S0026-4784.16.03977-0.
Marmiroli P, Riva B, Pozzi E, Ballarini E, Lim D, Chiorazzi A, Meregalli C, Distasi C, Renn CL, Semperboni S, Morosi L, Ruffinatti FA, Zucchetti M, Dorsey SG, Cavaletti G, Genazzani A, Carozzi VA. Susceptibility of different mouse strains to oxaliplatin peripheral neurotoxicity: Phenotypic and genotypic insights . PLoS One. 2017 Oct 11;12(10):e0186250. doi: 10.1371/journal.pone.0186250. eCollection 2017.
Marmiroli P, Scuteri A, Cornblath DR, Cavaletti G. Pain in chemotherapy-induced peripheral neurotoxicity. J Peripher Nerv Syst. 2017 Sep;22(3):156-161. doi: 10.1111/jns.12226.
Melcangi RC, Santi D, Spezzano R, Grimoldi M, Tabacchi T, Fusco ML, Diviccaro S, Giatti S, Carrà G, Caruso D, Simoni M, Cavaletti G. Neuroactive steroid levels and psychiatric and andrological features in post-finasteride patients. J Steroid Biochem Mol Biol. 2017 Jul;171:229-235. doi: 10.1016/j.jsbmb.2017.04.003.
Meroni R, Alberti P, Boria P, Giordano S, Cavaletti G. Distal pain and carpal tunnel syndrome diagnosis among cashiers: a longitudinal study. Int Arch Occup Environ Health. 2017 Nov;90(8):741-746. doi: 10.1007/s00420-017-1237-8. Epub 2017 Jun 20. Erratum in: Int Arch Occup Environ Health. 2017 Nov;90(8):747-750.
Monfrini M, Donzelli E, Rodriguez-Menendez V, Ballarini E, Carozzi VA, Chiorazzi A, Meregalli C, Canta A, Oggioni N, Crippa L, Avezza F, Silvani S, Bonandrini B, Figliuzzi M, Remuzzi A, Porretta-Serapiglia C, Bianchi R, Lauria G, Tredici G, Cavaletti G, Scuteri A. Therapeutic potential of Mesenchymal Stem Cells for the treatment of diabetic peripheral neuropathy. Exp Neurol. 2017 Feb;288:75-84. doi: 10.1016/j.expneurol.2016.11.006.
Parlanti P, Cappello V, Brun F, Tromba G, Rigolio R, Tonazzini I, Cecchini M, Piazza V, Gemmi M. Size and specimen-dependent strategy for x-ray micro-ct and tem correlative analysis of nervous system samples. Sci Rep. 2017 Jun 6;7(1):2858. doi: 10.1038/s41598-017-02998-1.
Schültke E, Balosso J, Breslin T, Cavaletti G, Djonov V, Esteve F, Grotzer M, Hildebrandt G, Valdman A, Laissue J. Microbeam radiation therapy – grid therapy and beyond: a clinical perspective. Br J Radiol. 2017 Oct;90(1078):20170073. doi: 10.1259/bjr.20170073.
Van Helleputte L, Kater M, Cook DP, Eykens C, Rossaert E, Haeck W, Jaspers T, Geens N, Vanden Berghe P, Gysemans C, Mathieu C, Robberecht W, Van Damme P, Cavaletti G, Jarpe M, Van Den Bosch L. Inhibition of histone deacetylase 6 (HDAC6) protects against vincristine-induced peripheral neuropathies and inhibits tumor growth. Neurobiol Dis. 2017 Nov 29;111:59-69. doi: 10.1016/j.nbd.2017.11.011.
Wozniak KM, Vornov JJ, Wu Y, Liu Y, Carozzi VA, Rodriquez-Menendez V, Ballarini E, Alberti P, Pozzi E, Semperboni S, Cook BM, Littlefield BA, Nomoto K, Condon K, Eckley S, DesJardins C, Wilson L, Jordan MA, Feinstein SC, Cavaletti G, Polydefkis M, Slusher BS.Peripheral neuropathy induced by microtubule-targeted chemotherapies: insights into acute injury and long-term recovery. Cancer Res . 2017 Nov 30. pii: canres.1467.2017. doi: 10.1158/0008-5472.CAN-17-1467.
2016
Alberti P, Parma M, Pioltelli P, Pogliani EM, Terruzzi E, Stasia A, Doni E, Cecchetti C, Cavaletti G. Severe, reversible nelarabine-induced neuropathy and myelopathy. J Peripher Nerv Syst. 2016 Sep; 21(3):154-6. doi: 10.1111/jns.12173.
Avallone G, Roccabianca P, Crippa L, Lepri E, Brunetti B, Bernardini C, Forni M, Olandese A, Sarli G. Histological Classification and Immunohistochemical Evaluation of MDM2 and CDK4 Expression in Canine Liposarcoma. Vet Pathol. 2016 Jul; 53(4):773-80. doi: 10.1177/0300985815626573.
Arosio A, Sala G, Rodriguez-Menendez V, Grana D, Gerardi F, Lunetta C, Ferrarese C, Tremolizzo L. MEF2D and MEF2C pathways disruption in sporadic and familial ALS patients. Mol Cell Neurosci. 2016 Jul; 74:10-7. doi: 10.1016/j.mcn.2016.02.002.
Bacigaluppi S, Donzelli E, De Cristofaro V, Bragazzi NL, D’Amico G, Scuteri A, Tredici G. Human endothelial progenitor cells rescue cortical neurons from oxygen-glucose deprivation induced death. Neurosci Lett. 2016 Sep 19; 631:50-5. doi: 10.1016/j.neulet.2016.08.014.
Bentivegna A, Roversi G, Riva G, Paoletta L, Redaelli S, Miloso M, Tredici G, Dalprà L. The Effect of Culture on Human Bone Marrow Mesenchymal Stem Cells: Focus on DNA Methylation Profiles. Stem Cells Int. 2016; 2016:5656701. doi: 10.1155/2016/5656701.
Caccianiga G, Cambini A, Donzelli E, Baldoni M, Rey G, Paiusco A. Effects of laser biostimulation on the epithelial tissue for keratinized layer differentiation: an in vitro study. J Biol Regul Homeost Agents. 2016 Apr-Jun; 30 (2 Suppl 1):99-105.
Canta A, Chiorazzi A, Carozzi VA, Meregalli C, Oggioni N, Bossi M, Rodriguez-Menendez V, Avezza F, Crippa L, Lombardi R, de Vito G, Piazza V, Cavaletti G, Marmiroli P. Age-related changes in the function and structure of the peripheral sensory pathway in mice. Neurobiol Aging. 2016 Sep; 45:136-148. doi: 10.1016/j.neurobiolaging.2016.05.014.
Malacrida A, Maggioni D, Cassetti A, Nicolini G, Cavaletti G, Miloso M. Antitumoral Effect of Hibiscus sabdariffa on Human Squamous Cell Carcinoma and Multiple Myeloma Cells. Nutr Cancer. 2016 Oct; 68(7):1161-70. doi: 10.1080/01635581.2016.1208830.
Marra A, Rossi D, Pignataro L, Bigogno C, Canta A, Oggioni N, Malacrida A, Corbo M, Cavaletti G, Peviani M, Curti D, Dondio G, Collina S. Toward the identification of neuroprotective agents: g-scale synthesis, pharmacokinetic evaluation and CNS distribution of (R)-RC-33, a promising SIGMA1 receptor agonist. Future Med Chem. 2016; 8(3):287-95. doi: 10.4155/fmc.15.191.
Mezzapelle R, Rrapaj E, Gatti E, Ceriotti C, Marchis FD, Preti A, Spinelli AE, Perani L, Venturini M, Valtorta S, Moresco RM, Pecciarini L, Doglioni C, Frenquelli M, Crippa L, Recordati C, Scanziani E, de Vries H, Berns A, Frapolli R, Boldorini R, D’Incalci M, Bianchi ME, Crippa MP. Human malignant mesothelioma is recapitulated in immunocompetent BALB/c mice injected with murine AB cells. Sci Rep. 2016 Mar 10;6:22850. doi: 10.1038/srep22850.
Monfrini M, Donzelli E, Rodriguez-Menendez V, Ballarini E, Carozzi VA, Chiorazzi A, Meregalli C, Canta A, Oggioni N, Crippa L, Avezza F, Silvani S, Bonandrini B, Figliuzzi M, Remuzzi A, Porretta-Serapiglia C, Bianchi R, Lauria G, Tredici G, Cavaletti G, Scuteri A. Therapeutic potential of Mesenchymal Stem Cells for the treatment of diabetic peripheral neuropathy. Exp Neurol. 2017 Feb; 288:75-84. doi: 10.1016/j.expneurol.2016.11.006.
Pachman DR, Qin R, Seisler D, Smith EM, Kaggal S, Novotny P, Ruddy KJ, Lafky JM, Ta LE, Beutler AS, Wagner-Johnston ND, Staff NP, Grothey A, Dougherty PM, Cavaletti G, Loprinzi CL. Comparison of oxaliplatin and paclitaxel-induced neuropathy (Alliance A151505). Support Care Cancer. 2016 Dec; 24(12):5059-5068.
Redaelli S, Ceccon M, Antolini L, Rigolio R, Pirola A, Peronaci M, Gambacorti-Passerini C, Mologni L. Synergistic activity of ALK and mTOR inhibitors for the treatment of NPM-ALK positive lymphoma. Oncotarget. 2016 Nov 8;7(45):72886-72897. doi: 10.18632/oncotarget.12128
Rigolio R., Ballarini E., Grimoldi M., Gardinetti M., Di Sante G. Multiple Sclerosis Drug Therapy: from the Classical Pharmaceutical down to Cellular and Molecular Approach . 2016 BENTHAM e-Books series – Frontiers in Clinical Drug Research – CNS and Neurological Disorders, Vol. 4, 3-113, 2016. ISBN(PRINT): 978-1-68108-296-7, eISBN: 978-1-68108-295-0.
Roccabianca P, Avallone G, Rodriguez A, Crippa L, Lepri E, Giudice C, Caniatti M, Moore PF, Affolter VK. Cutaneous Lymphoma at Injection Sites: Pathological, Immunophenotypical, and Molecular Characterization in 17 Cats. Vet Pathol. 2016 Jul; 53(4):823-32. doi: 10.1177/0300985815623620.
Scuteri A, Cavaletti G. How can neuroplasticity be utilized to improve neuropathy symptoms? Expert Rev Neurother. 2016 Nov; 16(11):1235-1236.
Sprowl JA, Ong SS, Gibson AA, Hu S, Du G, Lin W, Li L, Bharill S, Ness RA, Stecula A, Offer SM, Diasio RB, Nies AT, Schwab M, Cavaletti G, Schlatter E, Ciarimboli G, Schellens JH, Isacoff EY, Sali A, Chen T, Baker SD, Sparreboom A, Pabla N. A phosphotyrosine switch regulates organic cation transporters. Nat Commun. 2016 Mar 16;7:10880. doi: 10.1038/ncomms10880.
Zhu J, Carozzi VA, Reed N, Mi R, Marmiroli P, Cavaletti G, Hoke A. Ethoxyquin provides neuroprotection against cisplatin-induced neurotoxicity. Sci Rep. 2016 Jun 28; 6:28861. doi: 10.1038/srep28861.
2015
Avan A, Postma TJ, Ceresa C, Avan A, Cavaletti G, Giovannetti E, Peters GJ. Platinum-induced neurotoxicity and preventive strategies: past, present, and future. Oncologist. 2015 Apr;20(4):411-32. doi: 10.1634/theoncologist.2014-0044.
Beretta S, Cuccione E, Versace A, Carone D, Riva M, Padovano G, Dell’Era V, Cai R, Monza L, Presotto L, Rousseau D, Chauveau F, Paternò G, Pappadà GB, Giussani C, Sganzerla EP, Ferrarese C. Cerebral collateral flow defines topography and evolution of molecular penumbra in experimental ischemic stroke. Neurobiol Dis. 2015 Feb;74:305-13. doi: 10.1016/j.nbd.2014.11.019.
Binda D, Cavaletti G, Cornblath DR, Merkies IS; CI-PeriNomS study group. Rasch-Transformed Total Neuropathy Score clinical version (RT-TNSc(©) ) in patients with chemotherapy-induced peripheral neuropathy. J Peripher Nerv Syst. 2015 Sep;20(3):328-32. doi: 10.1111/jns.12140.
Canta A, Pozzi E, Carozzi VA. Mitochondrial Dysfunction in Chemotherapy-Induced Peripheral Neuropathy (CIPN). Toxics. 2015 Jun 5;3(2):198-223. doi: 10.3390/toxics3020198.
Carone D, Librizzi L, Cattalini A, Sala G, Conti E, Cuccione E, Versace A, Cai R, Monza L, de Curtis M, Ferrarese C, Beretta S. Pravastatin acute neuroprotective effects depend on blood brain barrier integrity in experimental cerebral ischemia. Brain Res. 2015 Jul 30;1615:31-41. doi: 10.1016/j.brainres.2015.04.025.
Carozzi VA, Canta A, Chiorazzi A. Chemotherapy-induced peripheral neuropathy: What do we know about mechanisms? Neurosci Lett. 2015 Jun 2;596:90-107. doi: 10.1016/j.neulet.2014.10.014. Erratum in: Neurosci Lett. 2015 Jun 2;596():108.
Carozzi VA, Chiorazzi A, Canta A, Meregalli C, Oggioni N, Cavaletti G, Marmiroli P. Chemotherapy-induced peripheral neurotoxicity in immune-deficient mice: new useful ready-to-use animal models. Exp Neurol. 2015 Feb;264:92-102. doi: 10.1016/j.expneurol.2014.11.002.
Caruso D, Abbiati F, Giatti S, Romano S, Fusco L, Cavaletti G, Melcangi RC. Patients treated for male pattern hair with finasteride show, after discontinuation of the drug, altered levels of neuroactive steroids in cerebrospinal fluid and plasma. J Steroid Biochem Mol Biol. 2015 Feb;146:74-9. doi: 10.1016/j.jsbmb.2014.03.012.
Cavaletti G, Alberti P, Marmiroli P. Chemotherapy-induced peripheral neurotoxicity in cancer survivors: an underdiagnosed clinical entity? Am Soc Clin Oncol Educ Book. 2015:e553-60. doi: 10.14694/EdBook_AM.2015.35.e553.
Cavaletti G, Marmiroli P. Chemotherapy-induced peripheral neurotoxicity. Curr Opin Neurol. 2015 Oct;28(5):500-7. doi: 10.1097/WCO.0000000000000234.
Cermenati G, Audano M, Giatti S, Carozzi V, Porretta-Serapiglia C, Pettinato E, Ferri C, D’Antonio M, De Fabiani E, Crestani M, Scurati S, Saez E, Azcoitia I, Cavaletti G, Garcia-Segura LM, Melcangi RC, Caruso D, Mitro N. Lack of sterol regulatory element binding factor-1c imposes glial Fatty Acid utilization leading to peripheral neuropathy. Cell Metab. 2015 Apr 7;21(4):571-83. doi: 10.1016/j.cmet.2015.02.016.
Chiorazzi A, Semperboni S, Marmiroli P. Current View in Platinum Drug Mechanisms of Peripheral Neurotoxicity. Toxics. 2015 Aug 7;3(3):304-321. doi: 10.3390/toxics3030304.
De Vito G, Canta A, Marmiroli P, Piazza V. A large-field polarisation-resolved laser scanning microscope: applications to CARS imaging. J Microsc. 2015 Nov;260(2):194-9. doi: 10.1111/jmi.12282.
Giatti S, Rigolio R, Romano S, Mitro N, Viviani B, Cavaletti G, Caruso D, Garcia-Segura LM, Melcangi RC. Dihydrotestosterone as a Protective Agent in Chronic Experimental Autoimmune Encephalomyelitis. Neuroendocrinology. 2015;101(4):296-308. doi: 10.1159/000381064.
Maggioni D, Monfrini M, Ravasi M, Tredici G, Scuteri A. Neurobasal medium toxicity on mature cortical neurons. Neuroreport. 2015 Apr 15;26(6):320-4. doi: 10.1097/WNR.0000000000000343.
Marmiroli P, Cavaletti G, Carozzi V, Riva B, Lim D, Genazzani AA. Calcium-related neurotoxicity of oxaliplatin: understanding the mechanisms to drive therapy. Curr Med Chem. 2015;22(32):3682-94.
Marmiroli P, Cavaletti G. Drugs for the treatment of peripheral neuropathies. Expert Opin Pharmacother. 2016;17(3):381-94. doi: 10.1517/14656566.2016.1120719. .
Meregalli C, Carozzi VA, Sala B, Chiorazzi A, Canta A, Oggioni N, Rodriguez-Menendez V, Ballarini E, Ceresa C, Nicolini G, Crippa L, Orciani M, Cavaletti G, Marmiroli P. Bortezomib-induced peripheral neurotoxicity in human multiple myeloma-bearing mice. J Biol Regul Homeost Agents. 2015 Jan-Mar;29(1):115-24.
Meregalli C. An Overview of Bortezomib-Induced Neurotoxicity. Toxics. 2015 Jul 27;3(3):294-303. doi: 10.3390/toxics3030294.
Mitro N, Cermenati G, Audano M, Giatti S, D’Antonio M, Fabiani ED, Crestani M, Saez E, Azcoitia I, Cavaletti G, Garcia-Segura LM, Melcangi RC, Caruso D. The lipogenic regulator Sterol Regulatory Element Binding Factor-1c is required to maintain peripheral nerve structure and function. Springerplus. 2015 Jun 12;4(Suppl 1):L45. doi: 10.1186/2193-1801-4-S1-L45. eCollection 2015.
Nicolini G, Monfrini M, Scuteri A. Axonal Transport Impairment in Chemotherapy-Induced Peripheral Neuropathy. Toxics. 2015 Aug 7;3(3):322-341. doi: 10.3390/toxics3030322. Review.
Nobile-Orazio E, Cocito D, Jann S, Uncini A, Messina P, Antonini G, Fazio R, Gallia F, Schenone A, Francia A, Pareyson D, Santoro L, Tamburin S, Cavaletti G, Giannini F, Sabatelli M, Beghi E; IMC Trial Group. Frequency and time to relapse after discontinuing 6-month therapy with IVIg or pulsed methylprednisolone in CIDP. J Neurol Neurosurg Psychiatry. 2015 Jul;86(7):729-34. doi: 10.1136/jnnp-2013-307515.
Othman A, Bianchi R, Alecu I, Wei Y, Porretta-Serapiglia C, Lombardi R, Chiorazzi A, Meregalli C, Oggioni N, Cavaletti G, Lauria G, von Eckardstein A, Hornemann T. Lowering plasma 1-deoxysphingolipids improves neuropathy in diabetic rats. Diabetes. 2015 Mar;64(3):1035-45. doi: 10.2337/db14-1325.
Redaelli S, Perini P, Ceccon M, Piazza R, Rigolio R, Mauri M, Boschelli F, Giannoudis A, Gambacorti-Passerini C. In vitro and in vivo identification of ABCB1 as an efflux transporter of bosutinib. J Hematol Oncol. 2015 Jul 7;8:81. doi: 10.1186/s13045-015-0179-4.
Scuteri A, Donzelli E, Rigolio R, Ballarini E, Monfrini M, Crippa L, Chiorazzi A, Carozzi V, Meregalli C, Canta A, Oggioni N, Tredici G,Cavaletti G. Therapeutic Administration of Mesenchymal Stem Cells Abrogates the Relapse Phase in Chronic Relapsing-Remitting EAE. J Stem Cell Res Ther 2015 Jan 5:262. doi:10.4172/2157-7633.1000262
Scuteri A, Ravasi M, Monfrini M, Milano A, D’Amico G, Miloso M, Tredici G. Human Mesenchymal Stem Cells Protect Dorsal Root Ganglia from the Neurotoxic Effect of Cisplatin. Anticancer Res. 2015 Oct;35(10):5383-9.
Spelzini F, Manodoro S, Frigerio M, Nicolini G, Maggioni D, Donzelli E, Altomare L, Farè S, Veneziano F, Avezza F, Tredici G, Milani R. Stem cell augmented mesh materials: an in vitro and in vivo study. Int Urogynecol J. 2015 May;26(5):675-83. doi: 10.1007/s00192-014-2570-z.
Tambalo S*, Peruzzotti-Jametti L*, Rigolio R*, Fiorini S, Bontempi P, Mallucci G, Balzarotti B, Marmiroli P, Sbarbati A, Cavaletti G, Pluchino S, Marzola P. Functional Magnetic Resonance Imaging of Rats with Experimental Autoimmune Encephalomyelitis Reveals Brain Cortex Remodeling. J Neurosci. 2015 Jul 8;35(27):10088-100. doi: 10.1523/JNEUROSCI.0540-15.2015. *co-authorship
Terrazzino S, Argyriou AA, Cargnin S, Antonacopoulou AG, Briani C, Bruna J, Velasco R, Alberti P, Campagnolo M, Lonardi S, Cortinovis D, Cazzaniga M, Santos C, Kalofonos HP, Canonico PL, Genazzani AA, Cavaletti G. Genetic determinants of chronic oxaliplatin-induced peripheral neurotoxicity: a genome-wide study replication and meta-analysis. J Peripher Nerv Syst. 2015 Mar;20(1):15-23. doi: 10.1111/jns.12110.
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