Gabriella Nicolini
Gabriella Nicolini

Assistant Professor
PhD
+39 02 6448 8047
gabriella.nicolini@unimib.it

SCOPUS Author ID: 7006333938, ORCID ID: 0000-0002-6241-4538

EDUCATION

Master’s degree in Biological Sciences, PhD in Morphology Sciences

POSITIONS

Assistant professor of Histology, University of Milano-Bicocca, Monza.
Coordinator of the Dental Hygiene degree course
Member of board of teachers of neuroscience PhD, School of Medicine Department, University of Milan-Bicocca
Head of Unit-University of Milan-Bicocca for Inter-University Center for the Promotion of the 3Rs Principles in Teaching & Research

PUBLICATIONS

Author of 65 peer-reviewed papers (Scopus h-index = 28), 6 book chapters (2 international scientific texts, 1 embryology textbook, 4 histology textbooks)

SELECTED PUBLICATIONS
  • Giambra M, Di Cristofori A, Raimondo F, Rigolio R, Conconi D, Chiarello G, Tabano SM, Antolini L, Nicolini G, Bua M, Ferlito D, Carrabba G, Giussani CG, Lavitrano M, Bentivegna A. Vacuolar Proton-Translocating ATPase May Take Part in the Drug Resistance Phenotype of Glioma Stem Cells. Inter. J. Mol. Sci. (2024) Febr. 27; 25, 2743. https://doi.org/10.3390/ijms25052743.
  • Tarasiuk O, Molteni L, Malacrida A, Nicolini G. The Role of NMNAT2/SARM1 in Neuropathy Development. Biology (Basel). 2024 Jan 22;13(1):61. doi: 10.3390/biology13010061. PMID: 38275737; PMCID: PMC10813049.
  • De Santo M, Giovinazzo M, Fava M, Mazzotta E, De Napoli IE, Greco M, Comandè A, Nigro A, Argurio P, Perrotta I, Davoli M, Tagarelli A, Elliani R, Granato T, Nicolini G, Chiorazzi a, Semperboni S, Ballarini E, Crocamo C, Cavaletti G, Lombardo D, Sisci D, Morelli C, Leggio A, Pasqua L.Engineered mesoporous silica-based nanoparticle as smart chemeotherapy nanodevice for bortezomib administration. Mater Chem Front. 2022; Dii:10.1039/d2qm01009g
  • Malacrida M, Di Domizio A, Bentivegna A, Tabano SM, Cislaghi G, Messuti E, Tabano S.M., Giussani C, Zuliani V, Rivara M, Nicolini G. MV1035 Overcomes Temozolomide Resistance in Patient-Derived Glioblastoma Stem Cell Lines. Biology 2022, 11(1), 70;
  • Tudda A, Donzelli E., Nicolini G., Semperboni S, Bossi M., Cavaletti G., Castriconi R., Mangili P., Del Vecchio A, Sarno A., Mettivier G., Russo P. (2021) Breast radiotherapy with kilovoltage photons and gold nanoparticles as radiosensitizer: an in vitro study. Medical Physics: doi: 10.1002/mp.15348.
  • Malacrida A, Semperboni S, Di Domizio A, Palmioli A, Broggi L, Airoldi C, Meregalli C, Cavaletti G, Nicolini G. (2021). Tubulin binding potentially clears up Bortezomib and Carfilzomib differential neurotoxic effect. Sci Rep. 2021; 11(1):10523. doi: 10.1038/s41598-021-89856-3.
  • Palmioli A, Nicolini G., Tripodi F, Orsato A, Ceresa C, Donzelli E, Arici M, Coccetti P, Rocchetti M, La Ferla B, Airoldi C. (2021) Targeting GRP receptor: Design, synthesis and preliminary biological characterization of new non-peptide antagonists of bombesin. Bioorg Chem. 2021; 104739. doi: 10.1016/j.bioorg.2021.104739.
  • Malacrida A, Rivara M, Di Domizio A, Cislaghi G, Miloso M, Zuliani V, Nicolini G. 3D proteome-wide scale screening and activity evaluation of a new ALKBH5 inhibitor in U87 glioblastoma cell line. Bioorg Med Chem. 2020; 28(4):115300. doi: 10.1016/j.bmc.2020.115300.
  • Ceresa C, Nicolini G, Semperboni S, Gandin V, Monfrini M, Avezza F, Alberti P, Bravin A, Pellei M, Santini C, Cavaletti G Evaluation of the Profile and Mechanism of Neurotoxicity of Water-Soluble [Cu(P)4]PF6 and [Au(P)4]PF6 (P = thp or PTA) Anticancer Complexes..Neurotox Res. 2018; 34(1):93-108.
MAIN FIELDS OF INTEREST
  • Chemotherapy-induced peripheral neurotoxicity (CIPN) (in vitro and in vivo models).
  • In vitro screening and characterization of possible new synthetized neuroprotective agents.
  • Development of new drugs and innovative strategies for glioblastoma treatment.
  • Biological effects of synchrotron radiation and X ray-based imaging
GRANTS

2023-ongoing. Funding: Filippo Serpero Pharmacological Institute Foundation
Project “Histone deacetylase 6 (HDAC6) inhibitors: possible neuroprotectors for chemotherapy-induced peripheral neuropathy”
Role: Principal Investigator

2022-ongoing. Funding: Giovanni Celeghin Onlus Foundation against brain tumors
Project “Multidisciplinary Approach to Optimize The Promising Anti Glioblastoma Candidate MV1035“.
Role: Principal Investigator

2010-2013 Italian Ministry of Research (RBFR081BZQ)
Project: “Development of a new device for neonatal liquid ventilation and evaluation of biological and biomechanical effects induced on the respiratory system”
Role: unit leader

EDITORIAL ACTIVITY

Editorial Board Member of “Biology” (MDPI)

INDUSTRIAL COLLABORATIONS

Italfarmaco S.p.A. (Italy)

Gabriella Nicolini