PostDoc fellow
PhD
+39 02 6448 8177
eleonora.pozzi@unimib.it
Born in 1991. She graduated in Biotechnology (Bachelor’s degree) in 2013 and in Biology (Master degree cum laude) in 2016 at the University of Milano Bicocca.
Since 2014 she has been collaborating in in vivo research projects on Chemotherapy-Induced Peripheral Neurotoxicity at Experimental Neurology Unit (University of Milano Bicocca), where now she attends the Ph.D. program in Neuroscience.
Her main expertise is in the development and use of in vivo experimental models to study the peripheral neuropathies.
She is author of 8 scientific papers on International peer-reviewed journals.
RESEARCH INTERESTS
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Preclinical assessment of chemotherapy-induced peripheral neurotoxicity
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Neuroprotection studies in chemotherapy-induced peripheral neuropathies (CIPN) models
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Study of molecular mechanisms involved in antineoplastic-induced peripheral neurotoxicity
PUBLICATIONS
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Alberti P., Canta A., Chiorazzi A., Fumagalli G., Meregalli C., Monza L., Pozzi E., Ballarini E., Rodriguez-Menendez V., Oggioni N., Sancini G., Marmiroli P., Cavaletti G. Topiramate prevents oxaliplatin-related axonal hyperexcitability and oxaliplatin induced peripheral neurotoxicity. Neuropharmacology (2019 Dec) 4:107905; DOI: 10.1016/j.neuropharm.2019.107905
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Potenzieri A., Riva B., Rigolio R., Chiorazzi A., Pozzi E., Ballarini E., Cavaletti G., Genazzani A. Oxaliplatin induced neuropathy occurs through impairment of haemoglobin proton buffering and is reversed by carbonic anhydrase inhibitors. Pain (2019 Oct); DOI: 10.1097/j.pain.0000000000001722
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Chiorazzi A., Wozniak K., Rais R., Wu Y., Gadiano A., Farah M., Liu Y., Canta A., Alberti P., Rodriguez-Menendez V., Meregalli C., Fumagalli G., Monza L., Pozzi E., Vornov J., Polydefkis M., Pietra C., Slusher B., Cavaletti G. Ghrelin agonist HM01 attenuates chemotherapy-induced neurotoxicity in rodent models. European Journal of Pharmacology (2018 Dec) 840:89-103; DOI: 10.1016/j.ejphar.2018.09.029
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Meregalli C., Fumagalli G., Alberti P., Canta A., Carozzi VA., Chiorazzi A., Monza L., Pozzi E., Sandelius Å., Blennow K., Zetterberg H., Marmiroli P., Cavaletti G. Neurofilament light chain as disease biomarker in a rodent model of chemotherapy induced peripheral neuropathy. Experimental Neurology (2018 Sep) 307:129-132; DOI: 10.1016/j.expneurol.2018.06.005
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Meregalli C., Marjanovic I., Scali C., Monza L., Spinoni N., Galliani C., Brivio R., Chiorazzi A., Ballarini E., Rodriguez-Menendez V., Carozzi V., Alberti P., Fumagalli G., Pozzi E., Canta A., Quartu M., Briani C., Oggioni N., Marmiroli P., Cavaletti G.High-dose intravenous immunoglobulins reduce nerve macrophage infiltration and the severity of bortezomib-induced peripheral neurotoxicity in rats. Journal of Neuroinflammation (2018 Aug) 15(1):232; DOI: 10.1186/s12974-018-1270-x
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Wozniak KM., Vornov JJ., Wu Y., Liu Y., Carozzi VA., Rodriquez-Menendez V., Ballarini E., Alberti P., Pozzi E., Semperboni S., Cook BM., Littlefield BA., Nomoto K., Condon K., Eckley S., DesJardins C., Wilson L., Jordan MA., Feinstein SC., Cavaletti G., Polydefkis M., Slusher BS. Peripheral Neuropathy Induced by Microtubule-Targeted Chemotherapies: Insights into Acute Injury and Long-term Recovery. Cancer Research (2017 Nov) pii: canres.1467.2017; DOI: 10.1158/0008-5472.CAN-17-1467
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Marmiroli P., Riva B., Pozzi E., Ballarini E., Lim D., Chiorazzi A., Meregalli C., Distasi C., Renn C., Semperboni S., Morosi L., Ruffinatti F., Zucchetti M., Dorsey S., Cavaletti G., Genazzani A., Carozzi VA. Susceptibility of different mouse strains to oxaliplatin peripheral neurotoxicity: Phenotypic and genotypic insights. Plos One (2017 Oct) 12(10):e0186250; DOI: 10.1371/journal.pone.0186250
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Canta A., Pozzi E., Carozzi V. Mitochondrial Dysfunction in Chemotherapy-Induced Peripheral Neuropathy (CIPN). Toxics (2015 Jun) 3(2):198–223, 2015; DOI: 10.3390/toxics3020198
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